Molecular Biophysics and Pharmacology

Lasorsa, A., Stuchlikova, O., Brabec, V., Natile, G., Arnesano, F. (2016), Activation of Platinum(IV) Prodrugs by Cytochrome c and Characterization of the Protein Binding Sites, MOLECULAR PHARMACEUTICS 13, 3216-3223

Pracharova, J., Muchova, TR., Tomastikova, ED., Intini, FP., Pacifico, C., Natile, G., Kasparkova, J., Brabec, V. (2016), Anticancer potential of a photoactivated transplatin derivative containing the methylazaindole ligand mediated by ROS generation and DNA cleavage, DALTON TRANSACTIONS 45, 13179-13186

Medrikova, Z., Novohradsky, V., Zajac, J., Vrana, O., Kasparkova, J., Bakandritsos, A., Petr, M., Zboril, R., Brabec, V. (2016), Enhancing Tumor Cell Response to Chemotherapy through the Targeted Delivery of Platinum Drugs Mediated by Highly Stable, Multifunctional Carboxymethylcellulose-Coated Magnetic Nanoparticles, CHEMISTRY-A EUROPEAN JOURNAL 22, 9750-9759

Brabec, V., Kasparkova, J., Kostrhunova, H., Farrell, NP. (2016), Inhibition of nuclear factor kappaB proteins-platinated DNA interactions correlates with cytotoxic effectiveness of the platinum complexes, SCIENTIFIC REPORTS 6

Vrana, O., Novohradsky, V., Medrikova, Z., Burdikova, J., Stuchlikova, O., Kasparkova, J., Brabec, V. (2016), Internalization of Ineffective Platinum Complex in Nanocapsules Renders It Cytotoxic, CHEMISTRY-A EUROPEAN JOURNAL 22, 2728-2735

Malina, J., Hannon, MJ., Brabec, V. (2016), Iron(II) supramolecular helicates interfere with the HIV-1 Tat-TAR RNA interaction critical for viral replication, SCIENTIFIC REPORTS 6

Brabec, V., Pracharova, J., Stepankova, J., Sadler, PJ., Kasparkova, J. (2016), Photo-induced DNA cleavage and cytotoxicity of a ruthenium(II) arene anticancer complex, JOURNAL OF INORGANIC BIOCHEMISTRY 160, 149-155

Zajac, J., Kostrhunova, H., Novohradsky, V., Vrana, O., Raveendran, R., Gibson, D., Kasparkova, J., Brabec, V. (2016), Potentiation of mitochondrial dysfunction in tumor cells by conjugates of metabolic modulator dichloroacetate with a Pt(IV) derivative of oxaliplatin, JOURNAL OF INORGANIC BIOCHEMISTRY 156, 89-97

Raveendran, R., Braude, JP., Wexselblatt, E., Novohradsky, V., Stuchlikova, O., Brabec, V., Gandin, V., Gibson, D. (2016), Pt(IV) derivatives of cisplatin and oxaliplatin with phenylbutyrate axial ligands are potent cytotoxic agents that act by several mechanisms of action, CHEMICAL SCIENCE 7, 2381-2391

Parajdi-Losonczi, PL., Benyei, AC., Kovats, E., Timari, I., Muchova, TR., Novohradsky, V., Kasparkova, J., Buglyo, P. (2016), [(eta(6)-p-cymene)Ru(H2O)(3)](2+) binding capability of aminohydroxamates - A solution and solid state study, JOURNAL OF INORGANIC BIOCHEMISTRY 160, 236-245