Department of Molecular Biophysics and Pharmacology

 

Head: Viktor Brabec

Scientific interests:

  • Molecular and cellular mechanisms of action of anticancer and antimicrobial metallodrugs
    DNA and RNA interactions with compounds of biological significance
    DNA synthesis and DNA repair
    Raman, circular/linear dichroism spectroscopy and microcalorimetry of nucleic acids and proteins

 

The main research objective of the Department is to increase knowledge and understanding of the mechanisms of biological (antitumor and antibiotic) action of metallodrugs and to use this enhanced knowledge to develop new classes of metallodrugs with truly novel mechanisms of action and novel spectra of biomedical activity.