Molecular Biophysics and Pharmacology

Sofia Sharkawy, Alba Hernández-García, Hana Kostrhunova, Delia Bautista, Lenka Markova, María Dolores Santana, Jana Kasparkova, Viktor Brabec, José Ruiz (2025), A novel benzothiazole-1,2,3-triazole-based arene osmium(ii) complex as an effective rhabdomyosarcoma cancer stem cell agent, Inorganic Chemistry Frontiers

Jaroslav Malina, Hana Kostrhunova, Janice R. Aldrich-Wright, Viktor Brabec (2025), Antitumor platinum(II) complex 56MESS binds to DNA G-quadruplexes, downregulates expression of c-MYC and k-RAS oncogenes, and triggers DNA damage in cancer cells, Chemico-Biological Interactions

Vojtech Novohradsky, Tomer Babu, Hana Kostrhunova, Menucha Plaskow, Lenka Markova, Sourav Acharya, Dan Gibson, Viktor Brabec (2025), Cisplatin-eugenol Pt(IV) prodrugs target colon cancer stem cells: A novel strategy for enhanced anticancer efficacy, Biomedicine & Pharmacotherapy

Sofia Sharkawy, Sourav Acharya, Hana Kostrhunová, Moumita Maji, Lenka Marková, Vojtěch Novohradský, Dan Gibson, Viktor Brabec (2025), Crizotinib- or Ceritinib-Conjugated Platinum(IV) Prodrugs As Potent Multiaction Agents Inducing Antiproliferative Effects in 2D and 3D Cancer Cell Models, Journal of Medicinal Chemistry

Huayun Shi, Jana Kasparkova, Fortuna Ponte, Hana Kostrhunova, Guy J. Clarkson, Emilia Sicilia, Viktor Brabec, Peter J. Sadler (2025), Excited-State Cis and Trans Pt(IV) Diamine Anticancer Complexes, Inorganic Chemistry

Vojtech Novohradsky, Alicia Marco, Marie Svitelova, Natalia Cutillas, José Ruiz, Viktor Brabec (2025), Photoactivatable Cyclometalated Ir(III) Compound Penetrates the Blood-Brain Barrier in 3D Spheroidal and Advanced 3D Organoid Models of Inherently Resistant and Aggressive Brain Tumors, ACS Pharmacology & Translational Science

Vojtech Novohradsky, Alicia Marco, Marie Svitelova, Natalia Cutillas, José Ruiz, Viktor Brabec (2025), Photoactivatable Cyclometalated Ir(III) Compound Penetrates the Blood-Brain Barrier in 3D Spheroidal and Advanced 3D Organoid Models of Inherently Resistant and Aggressive Brain Tumors, ACS Pharmacology & Translational Science

Petra Andršová, Jitka Prachařová, Vojtěch Novohradský, Slavomíra Šterbinská, Pavel Štarha, Jana Kašpárková, Viktor Brabec (2025), Phototoxicity of Half-Sandwich Rhodium(III) Complexes with Anthracene and Biphenyl Substituents toward Mammalian Cancer Cells and Multicellular Tumor Spheroids, Journal of Medicinal Chemistry