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Czech-Norwegian Research Programme (CZ09)
Project title: Nuclear Architecture in the regulation of autophagy, DNA repair and gene expression
Project No.: 7F14369 (2014-2017)
Acronym: NuArch
NuArch is based on the hypothesis that nuclear structural proteins, in addition to their roles in gene expression regulation, are also implicated in autophagy and DNA damage repair. Defects in these proteins are likely results in defective autophagy and DDR signaling, with important implications for cellular homeostasis and the regulation of cell and tissue growth.
NuArch is expected to establish new roles for known nuclear structural proteins and link them to key nuclear processes critical for cellular homeostasis and regulation of cell and tissue growth. It will also shed a new light on several nuclear proteins known to be implicated in a variety of rare diseases collectively referred to as “nuclear envelopathies”.
Principal investigator (project coordinator):
assoc. prof. Eva Bártová, Ph.D. (Czech Republic)
Contact: Institute of Biophysics of the CAS, v. v. i.
Královopolská 135
612 65 Brno
Telephone: +420541517141
email:bartova@ibp.cz
Curriculum Vitae
List of Project Promoter’s team staff
| First name | Surname | Position in project |
| Eva | Bártová | Project promoter |
| Soňa | Legartová | Postdoc |
| Stanislav | Kozubek | Director of IBP |
| Lenka | Stixová | Research scientist |
| Jana | Krejčí | Research scientist |
| Jana | Suchánková | PhD student |
| Petra | Řezníčková-Podloučková (born Sehnalová) | PhD student |
| Michal | Franek | PhD student |
| Alena | Kovaříková | PhD student |
| Barbora | Malyšková | PhD student |
Project partners:
Prof. Anne Simonsen, Ph.D. (Norway)
email: anne.simonsen@medisin.uio.no
List of Project Partner’s team staff
| First name | Surname | Position in project |
| Anne | Simonsen | Project partner |
| Alf Håkon | Lystad | PhD student |
| Serhiy | Pankiv | Postdoc |
| Gunnveig T. | Bjørndal | Technician |
Prof. Philippe Collas, Ph.D. (Norway)
email: philippe.collas@medisin.uio.no
List of Project Partner’s team staff
| First name | Surname | Position in project |
| Philippe | Collas | Project Partner |
| Thomas | Küntziger | Postdoc |
| Graciela | Lopez Soop | PhD student |
| Akshay | Shah | PhD student |
| Anita | Sørensen | MS |
Czech-Norway meetings:
The Opposition Procedure
2nd Czech-Norwegian Research Conference – Prague 2016
Publication with dedication toproject:
Presentation withdedication toproject:
Krejčí, Černá Hora (Czech Republic), 2015, oral presentation
Bártová, PhD workshop 2015, Brno (Czech Republic), oral presentation
Experimental results:
Miscellaneous:
- import of cKO HDAC1 and cKO HDAC3 mice
