Home Research Departments DCBE Group of the Structure and Function of the Cell Nucleus Eva Bártová CV

Bártová Eva, Prof., RNDr., Ph.D., DSc.

ORCID: (https://orcid.org/0000-0003-1299-0470)

Born 16.1.1968 in Kaplice, district Český Krumlov, Czech Republic, as Eva Musilová

Affiliation: Institute of Biophysics, Academy of Sciences of the Czech Republic, Královopolská 135, 612 65 Brno, Czech Republic; tel.: +420541517141; e-mail: bartova@ibp.cz

 

Education, training, and employment:

  • 1991: graduated in Experimental Biology, Faculty of Sciences, Masaryk University Brno. Diploma thesis (Helmintofauna vodních ptáků ČR - Helminth Fauna of Waterbirds in Czechoslovakia), cooperation with prof. Milan Gelnar (mentor from Masaryk University) and prof. Tomáš Šolc (help with helminths’ determination), Institute of Parasitology, České Budějovice and Faculty of Science, Masaryk University Brno.
  • 1992-1995: Ph.D. study: Department of Animal Physiology, Faculty of Sciences, Masaryk University Brno. The experimental part of the Ph.D. study: Institute of Biophysics, Academy of Sciences of the Czech Republic, Brno, Laboratory of Cytokinetics and Flow-cytometry.
  • 1995-1997: Assistant professor at Faculty of Medicine, Department of Pathophysiology, Masaryk University Brno.
  • 1997-present:  Department of Molecular Cytology and Cytometry, renamed in 2022 to Department of Cell Biology and Epigenetics, Institute of Biophysics, Czech Academy of Sciences, Brno  
  • 2010: Associated professor of Genetics and Molecular Biology, Masaryk University Brno.
  • 2015-2017: a part-time job at the Institute of Cellular Biology and Pathology, 1st Faculty of Medicine, Charles University in Prague, Czech Republic. 2016-present: Department leader: Department of Molecular Cytology and Cytometry / Cell Biology and Epigenetics, Institute of Biophysics. Institute of  Biophysics of the Czech Academy of Sciences, Brno.
  • 2017-2027: Director of the Institute of Biophysics of the Czech Academy of Sciences, Brno.
  • 2019: DSc. - Research professor, with a scientific degree from the Czech Academy of Sciences
  • 2020: EMBO member 2020
  • 2024: Professor at Masaryk University - Molecular Biology and Genetics

In detail: I graduated from the Faculty of Science, Masaryk University with an MSc. degree in parasitology. During my studies, I focused on parasites of aquatic birds in collaboration with colleagues from the Institute of Parasitology of the Czech Academy of Sciences, in České Budějovice. Between 1988 and 1991, I regularly visited this institute through various internships and research activities, especially in the field of taxonomy. At that time, collaboration was established with Prof. František Moravec and Prof. Tomáš Scholz. However, after defending my diploma thesis (headed by Prof. Milan Gelnar), despite the long-term collaboration, I did not get a position at the Institute of Parasitology in České Budějovice and therefore began seeking employment at institutes of the Czech Academy of Sciences in Brno. After voluntary work at the Institute of Biophysics in 1991, I was employed there from January 1992 till September 1992; after that, I started my Ph.D. studies at the Faculty of Sciences, Masaryk University (former University of J. E. Purkyně), but my laboratory work was at the Institute of Biophysics. I defended my Ph.D. in 1995. After that, for two years, I was an assistant professor at the Faculty of Medicine, Masaryk University, Brno, Department of Pathophysiology. In 1997, after a short maternity leave, I was recruited as a young scientist at the Institute of Biophysics (IBP), where, in 2005, I established my laboratory focused on the structure of the cell nucleus and epigenetics. In 2010, I became an associate professor of Genetics and Molecular Biology at MU. Since 2016, I have been working as a department leader at the IBP. In 2016-2017, I completed my internship at the 1st Medical Faculty of Charles University in Prague, and in 2017, I became director of the Institute of Biophysics, Czech Acad. Sci. In 2018, I received a bronze medal from Masaryk University (MU), which was awarded to the 100 best students who graduated during the 100 years of MU's duration. I defended my Research Professor degree (DSc.)  in 2019, and in 2020 I was elected as a member of the European Molecular Biology Organization (EMBO member 2020), which is a prestigious award for scientists working in the field of molecular biology. In 2024, I became a professor at Masaryk University in Brno. So far, I have published more than 120 scientific papers; according to Google Scholar H-index is 36, and the number of citations is 4537 (15.5.2026). Under her leadership, more than 25 students defended their work, including ten dissertations. I work in two scientific councils of MU (the Faculty of Medicine and the Faculty of Sciences) and scientific councils of the Czech Academy of Sciences (2022-2025). In total, for eight years, I have been working on expert panels of the Czech Science Foundation (the highest grant authority in the Czech Republic), and annually I am an opponent of many students’ theses. Also, I am a member of the Molecular Biology Committee for doctoral dissertations at MU and the Biochemistry Committee at MU; and I also serve as an ad-hoc reviewer in many scientific journals, including NAR, Epigenetics & Chromatin, Epitranscriptomics, etc. As the director of the Institute of Biophysics, I support the work of parents with children, especially women in science. I established a scientific incubator for talented researchers. Also, established a kids’ corner at the institute and support a part-time job for parents with small children. Also, I worked for the Strategy AV21, a PR activity of the Czech Academy of Sciences.

My primary scientific focus is on epigenetics and DNA repair. Among my most significant contributions is the discovery of the role of the OCT4 protein in DNA repair processes in embryonic stem cells. My research team was also the first to investigate the function of N4-acetylcytidine (ac4C) in RNA when recruited to UVA-irradiated regions of the human genome. Earlier in my career, my team studied the three-dimensional organization and function of chromatin in tumor and embryonic stem cells undergoing different differentiation pathways. Methodologically, I have specialized in high-resolution cytometry and advanced imaging approaches, particularly confocal microscopy, immunofluorescence, living cell studies, and fluorescence in situ hybridization (FISH).

To investigate 3D genome organization, I participated in the European Union project "3D Genome," coordinated by Prof. Roel van Driel (The Netherlands). Within this project, I worked during a short-term visit in the laboratory of Prof. Christoph Cremer (Heidelberg, Germany), one of the pioneers of 4Pi super-resolution microscopy. Throughout my career, I have served as Principal Investigator of numerous national research projects, including approximately ten grants funded primarily by the Czech Science Foundation. I have also been Principal Investigator of a prestigious Marie Curie project, supported by the EU, and two projects supported by Norwegian funds. During the Marie Curie programme (2012–2014), I coordinated collaborative research involving Czech, Polish, and Russian scientists, and subsequently supervised Czech–Norwegian scientific cooperation for an additional three years. I was a member of the EU COST Action TD0905 "Epigenetics: Bench to Bedside" (2009–2014), which brought together leading epigenetics researchers from twenty European countries. Since 2025, I have been a member of the Czech–US bilateral Inter-Excellence project (LUAUS25085), focused on the effects of hormones on DNA damage response and RNA function. This project established a collaboration between the Institute of Biophysics of the Czech Academy of Sciences and the National Cancer Institute (NCI), part of the National Institutes of Health (NIH) in the USA. In addition to my research activities, I serve as the president of the Czech Biophysical Society, which collaborates closely with the International Union of Pure and Applied Biophysics (IUPAB) and the European Biophysical Societies' Association (EBSA). I have been invited to present my research at numerous international conferences, including the FEBS Meeting in St. Petersburg (2013), the Wilhelm Bernhard Workshop in Vienna (2015), the Meeting on Embryonic Stem Cell Biology in Eilat, Israel (2017), the Conference on the Epigenetics of Aging in Halle, Germany (2019), and the EMBO Members' Meeting in Heidelberg (2021). I also organize the annual conference of the Czech Biophysical Society. In 2026, this conference is organized in České Budějovice.

 

The list of scientific papers 

1. Hofmanová J., Musilová E., Kozubík A. (1996). Suppression of human cancer cell proliferation by lipoxigenase inhibitors and gamma-radiation in vitro. Gen. Physiol. Biophys. 15, 317-331. IF=0.69

2. Kozubík A., Hofmanova J., Dušek L., Musilová E. (1997) 5-lipoxigenase inhibitors potentiate effects of TGF-beta 1 on    the differentiation of human leukemia HL-60 cells. J. Leuk. Biol., 62, 240-248. IF=4.22

3. Bártová E., Španová A., Janáková L., Bobková M., Rittich B. (1997) Apoptotic damage of DNA in human leukaemic HL-60 cells treated with C2-ceramide was detected after G1 blockade of the cell cycle. Physiol. Res., 46, 155-160. IF=1.14*

4. Kozubek M., Kozubek S., Lukášová E., Marečková A., Bártová E., Skalníková M.,    Jergová A. (1999) High-resolution cytometry: Automated 2-D and 3-D analysis of hybridization dots in interphase cell nuclei using multi-color FISH and CCD microscopy. Cytometry, 36, 279-293. IF=2.7

5. Lukášová E., Kozubek S., Kozubek M., Kroha V., Marečková A., Skalníková M., Bártová E., Šlotová J. (1999) Chromosomes participating in translocations typical of malignant haemoblastosis are also involved in exchange aberrations induced by fast neutrons. Radiat. Res., 151, 375-384. IF=3.23

6. Kozubek S., Lukášová E.,  Marečková A., Skalníková M., Kozubek M., Bártová E. , Kroha V., Krahulcová E., Šlotová J. (1999) The topological organization of chromosomes 9 and 22 in cell nuclei has a determinative role in the induction of t(9;22) translocations and in the pathogenesis of t(9;22) leukemias. Chromosoma, 108, 426-435. IF=2.71

7. Bártová E., Kozubek S., Kozubek M., Jirsová P., Lukášová E., Skalníková M., Buchníčková K. (2000) The influence of the cell cycle, differentiation and irradiation on the nuclear location of the abl, bcr and c-myc genes in human leukemic cells. Leukemia Research, 24, 233-241. IF=1.5*

8. Bártová E., Kozubek S., Kozubek M., Jirsová P., Lukášová E., Skalníková M., Cafourková A., Koutná I. (2000) Nuclear topography of the c-myc gene in human leukemic cells. Gene, 244, 1-11. IF=2.5*

9. Koutná I., Kozubek S., Žaloudík J. Kozubek M., Lukášová E., Matula P., Bártová E., Skalníková M., Cafourková A., Jirsová P. (2000) Topography of genetic loci in tissue samples: towards new diagnostic tool using interphase FISH and high-resolution image analysis techniques.  Anal. Cell. Pathol. 20: (4) 173-185. IF=0.84

10. Skalníková M., Kozubek S., Lukášová E., Bártová E., Jirsová P., Cafourková A., Koutná I., Kozubek M. (2000) Spatial arrangement of genes, centromeres and chromosomes in human blood cell nuclei and its changes during the cell cycle, differentiation and after irradiation. Chromosome Res. 8: (6) 487-499. IF=1.73

11. Cafourková A., Lukášová E., Kozubek S., Kozubek M., Govorun R.D., Koutná I., Bártová E., Skalníková M., Jirsová P., Paseková R., Krasavin E.A. (2001) Exchange aberrations among 11 chromosomes of human lymphocytes induced by gamma-rays. Int. J. Radiat. Biol. 77: (4) 419-429. IF=2.36

12. Jirsová P., Kozubek S., Bártová E., Kozubek M., Lukášová E., Cafourková A., Koutná L., Skalníková M. (2001) Spatial distribution of selected genetic loci in nuclei of human  leukemia cells after irradiation. Radiat.  Res. 155: (2) 311-319. IF=2.45

13. Bártová E., Kozubek S., Jirsová P., Kozubek M., Lukášová E., Skalníková M., Cafourková A., Koutná I., Paseková R. (2001) Higher-order chromatin structure of human granulocytes. Chromosoma 110: 360-370. IF=3.29*

14. Kozubek M., Kozubek S., Lukášová E, Bártová E., Skalníková M., Matula P., Matula P., Jirsová P., Cafourková A., Koutná I. (2001) Combined confocal and wide-field high-resolution cytometry of fluorescent in situ hybridization-stained cells. Cytometry 45(1):1-12. IF=2.22

15. Bártová E., Kozubek S., Jirsová P., Kozubek M., Gajová H., Lukášová E., Skalníková M., Gaňová A., Koutná I., Hausmann M. (2002) Nuclear structure and gene activity in human differentiated cells. J. Struct. Biol. 139: 76-89. IF=4.2*

16. Kozubek S., Lukášová E., Jirsová P., Koutná I., Kozubek M., Gaňová A., Bártová E., Falk M., Paseková R. (2002) 3D structure of the human genome: order in randomness. Chromosoma 111: 321-331. IF=2.83

17. Taslerová R., Kozubek S., Lukášová E., Jirsová P., Bártová E., Kozubek M. (2002) Arrangement of chromosome 11 and 22 territories, EWSR1 and FLI1 genes, and other genetic elements of these chromosomes in human lymphocytes and Ewing sarcoma cells. Hum. Genet. 112(2):143-55. IF=3.43

18. Kozubek M., Skalníková M., Matula P., Bártová E., Rauch J., Neuhaus F., Eipel H., Hausmann M. (2002) Automated microaxial tomography of cell nuclei after specific labelling by fluorescence in situ hybridisation. Micron 33(7-8): 655-65. IF=1.54

19. Bártová E., Kozubek S., Gajová H., Jirsová P., Žlúvová J., Taslerová R., Koutná I., Kozubek M. (2003) Cytogenetics and cytology of retinoblastomas. J. Cancer Res. Clin. Oncol. 129(2):89-99.  IF=2.16*

20. Bártová E., Jirsová P., Fojtová M, Souček K., Kozubek S. (2003) Chromosomal territory segmentation in apoptotic cells. Cell Mol Life Sci.60(5): 979-990. IF=4.99*

21. Galiová G., Bártová E., Kozubek S. (2004) Nuclear topography of beta-like globin gene cluster in IL-3-stimulated human leukemic K-562 cells. Blood Cells Mol. Dis.  33, 4-14. IF=2.55*

22. Bártová E., Harničarová A., Pacherník J., Kozubek S. (2005) Nuclear topography and expression of the BCR/ABL fusion gene and its protein level influenced by cell differentiation and RNA interference. Leuk Res. 29, 901-913.  IF=2.24*

23. Bártová E., Pacherník J., Harničarová A., Kovařík A., Kovaříková M., Hofmanová J., Skalníková M., Kozubek M., Kozubek S. (2005) Nuclear levels and patterns of histone H3 modifications and HP1 proteins after inhibition of histone deacetylases. J.  Cell Sci. 118 (21), 5035-5046. IF= 6.91*

24. Bártová E., Kozubek S.  (2006)  Nuclear architecture in the light of gene expression and cell differentiation studies. Biol Cell. 98(6):323-36. Review. IF= 4.3*

25. Taslerová R., Kozubek S., Bártová E., Gajdušková P., Kodet R., Kozubek M.(2006) Localization of genetic elements of intact and derivative chromosome 11 and 22 territories in nuclei of Ewing sarcoma cells. J. Struct. Biol. 155(3):493-504. IF= 3.49

26. Harničarová A., Kozubek S., Pacherník J., Krejčí J., Bártová E. (2006) Distinct nuclear arrangement of active and inactive c-myc genes in control and differentiated colon carcinoma cells. Exp Cell Res.  312(20):4019-35. IF=3.77*

27. Skalníková M., Bártová E, Ulman V., Matula P., Svoboda D., Harničarová A., Kozubek M., Kozubek S. (2007) Distinct patterns of histone methylation and acetylation in human interphase nuclei. Physiol Res. 56(6):797-806. IF= 2.09*

28. Bártová E., Pacherník J., Kozubík A., Kozubek S. (2007) Differentiation-specific association of HP1alpha and HP1beta with chromocentres is correlated with clustering of TIF1beta at these sites. Histochem Cell Biol. 127(4):375-88. IF= 3.22*

29. Fojtova M., Piskala A., Votruba I., Otmar M., Bártová E., Kovařík A. (2007) Efficacy of DNA hypomethylating capacities of 5-aza-2'-deoxycytidine and its alpha anomer. Pharmacol. Res. 55(1):16-22. IF= 2.42

30. Koutná I., Krontorád P., Svoboda Z., Bártová E., Kozubek M., Kozubek S. (2007) New insights into gene positional clustering and its properties supported by large-scale analysis of various differentiation pathways. Genomics  89(1):81-8. IF= 3.56

31. Kroupová J., Bártová E., Fojt L., Strasák L., Kozubek S., Vetterl V. (2007) Low-frequency magnetic field effect on cytoskeleton and chromatin. Bioelectrochemistry 70(1):96-100. IF= 1.88*

32. Bártová E., Krejčí J., Harnicarová A., Kozubek S. (2008) Differentiation of human embryonic stem cells induces condensation of chromosome territories and formation of heterochromatin protein 1 foci. Differentiation. 76(1):24-32. IF= 3.75*

33. Bártová E., Harničarová A., Krejčí J., Strašák L. and Kozubek S. (2008) Single-cell c-myc gene expression in relationship to nuclear domains, accepted for publication in Chromosome Research, 6(2):325-43. IF=3.41*

34. Gabriela Galiová, Eva Bártová, Ivan Raška, Jana Krejčí and Stanislav Kozubek. (2008) Chromatin changes induced by lamin A/C deficiency and the HDAC inhibitor TSA. European Journal of Cell Biology, 87(5):291-303. IF=3.96*

35. Bártová E, Krejčí J, Harničarová A, Galiová G, Kozubek S. (2008) Histone Modifications and Nuclear Architecture: A Review. J Histochem Cytochem. 56(8):711-21. IF=2.82*

36. Krejčí J, Harničarová A, Kůrová J, Uhlířová R, Kozubek S, Legartová S, Hájek R, Bártová E.  (2008) Nuclear organization of PML bodies in leukaemic and multiple myeloma cells. Leuk. Res., 32(12):1866-77. IF=2.39*

37. Bártová E, Galiová G, Krejčí J, Harničarová A, Strašák L, and Kozubek S. (2008) Epigenome and chromatin structure in human embryonic stem cells undergoing differentiation. Developmental Dynamics. 237(12):3690-702. IF=3.02*

38. Bártová E., Krejčí J., Hájek R., Harničarová A., Kozubek S. (2008) Chromatin Structure and Epigenetics of Tumour Cells: a Review. Cardiovascular and Haematological Disorders - Drug target, Mar;9(1):51-61. Review. IF=0* 

39. Krejčí J., Uhlířová R., Galiová G., Kozubek S., Smogová J, Bártová E. (2009) Genome-wide reduction in H3K9 acetylation during human embryonic stem cell differentiation. Journal of Cellular Physiology, 219(3):677-87. IF=4.58.

40. Strašák L., Bártová E., Harničarová A., Galiová G., Krejčí J. nad Kozubek S. (2009) H3K9 acetylation influences radial chromatin positioning. Journal of Cellular Physiology, 220(1):91-101. IF=4.58*

41. Strašák L, Bártová E, Krejčí J, Fojt L, Vetterl V. (2009) Effects of ELF-EMF on brain proteins in mice. Electromagn Biol Med. 2009;28(1):96-104.IF=0.73

42. Epigenetics of multiple myeloma after treatment with cytostatics and gamma radiation. Krejčí J, Harničarová A, Štreitová D, Hájek R, Pour L, Kozubek S, Bártová E (2009) Leuk Res. 33(11):1490-8. IF=2.36*

43. Legartová S, Krejčí J, Harničarová A, Hájek R, Kozubek S, Bártová E. Nuclear topography of the 1q21 genomic region and Mcl-1 protein levels associated with pathophysiology of multiple myeloma. Neoplasma. 2009;56(5):404-13. IF=1.19*

44. Harničarová-Horáková A, Galiová G, Soňa L, Kozubek S, Matula P, Bártová E. (2010) Chromocentre integrity and epigenetic marks. J Struct Biol. 169(1):124-33. IF=3.50*

45. Uhlířová R, Harničarová Horáková A, Galiová G, Legartová S, Matula P, Fojtová M, Vařecha M, Amrichová J, Vondráček J,  Kozubek S, Bártová E. (2010) SUV39h- and A-type Lamin-Dependent Telomere Nuclear Rearrangement. J. Cellular Biochemistry, 109(5):915-26. IF=3.12*

46. Harničarová Horáková A., Bártová E., Galiová G., Uhlířová R., Matula P., Kozubek S. (2010) SUV39h-independent association of HP1β with fibrilarin-positive nucleolar region. Chromosoma, 119(3):227-41. IF=4.20*

47. Bártová E., Harničarová Horáková A., Uhlířová R., Raška I, Galiová G, Orlova D, Kozubek S. (2010) Structure and epigenetics of nucleoli in comparison with non-nucleolar compartments, J. Histochemistry & Cytochemistry, 58(5):391-403. IF=2.38*

48. Harničarová Horáková A, Bártová E, Kozubek S. (2010) Chromatin structure with respect to histone signature changes during cell differentiation. Cell Struct Funct. 35(1):31-44. Epub 2010 Apr 15. Review. IF=3.27*

49. Legartova S, Harnicarova-Horakova A, Bartova E, Hajek R, Pour L, Kozubek S. (2010)Expression of RAN, ZHX-2, and CHC1L genes in multiple myeloma patients and in myeloma cell lines treated with HDAC and Dnmts inhibitors. Neoplasma 57(5):482-7. IF=1.45*

50. Eva Bártová, Gabriela Galiová, Soňa Legartová, Lenka Stixová, Alžběta Jugová, Stanislav Kozubek. (2010) Genome instability in the context of chromatin structure and fragile sites. Critical Reviews in Eukaryotic Gene expression, 20(3):181-94. IF=4.11*

51. Bártová E, Stixová L, Galiová G, Horáková AH, Legartová S, Kozubek S. (2011) Mutant genetic background affects functional re-arrangement and kinetic properties of JMJD2B histone demethylase. J. Mol. Biol. 405(3):679-95. IF=4.01*

52. Darya Yu. Orlova, Eva Bártová , Valeri P. Maltsev, Stanislav Kozubek (2011) A non-fitting method employing a spatial sine window transform for inhomogeneous effective diffusion measurements by FRAP.  Biophysical Journal, 100(2):507-16. IF=4.22

53. Stixová L, Bártová E, Matula P, Daněk O, Legartová S, Kozubek S. (2011) Heterogeneity in the kinetics of nuclear proteins and trajectories of substructures associated with heterochromatin. Epigenetics and Chromatin 4:5. IF=4.73*

54. Jugova A, Sustackova G, Legartova S, Stixova L, Kozubek S, Bartova E. (2011) Effects of epigenetic-based anti-cancer drugs in leukemia and multiple myeloma cells. Cell Biol Int. 35(12):1195-203, IF=1.75*

55. Šustáčková G, Kozubek S, Stixová L, Legartová S, Matula P, Orlova D, Bártová E. (2011) Acetylation-dependent nuclear arrangement and recruitment of BMI1 protein to UV-damaged chromatin. J Cell Physiol. 227(5):1838-50; IF=4.0*

56. Šustáčková G, Legartová S, Kozubek S, Stixová L, Pacherník J, Bártová E. (2011) Differentiation-Independent Fluctuation of Pluripotency-Related Transcription Factors and Other Epigenetic Markers in Embryonic Stem Cell Colonies. Stem Cells Dev. 21(5):710-20. IF=4.79*

57. Bártová E, Šustáčková G, Stixová L, Kozubek S, Legartová S, Foltánková V. (2011) Recruitment of Oct4 protein to UV-damaged chromatin in embryonic stem cells. PLoS One. 2011;6(12):e27281. IF=4.3.

58. FOLTÁNKOVÁ V., LEGARTOVÁ S., KOZUBEK S., BÁRTOVÁ E. (2012) Tumor-specific histone signature and DNA methylation in multiple myeloma and leukemia cells. Neoplasma. 59(4):450-62.

59. Orlova DY, Stixová L, Kozubek S, Gierman HJ, Sustáčková G, Chernyshev AV, Medvedev RN, Legartová S, Versteeg R, Matula P, Stoklasa R, Bártová E. (2012) Arrangement of nuclear structures is not transmitted through mitosis but is identical in sister cells. J Cell Biochem. 113(11):3313-29. doi: 10.1002/jcb.24208.

60. Stixová L, Matula P, Kozubek S, Gombitová A, Cmarko D, Raška I, Bártová E. (2012) Trajectories and nuclear arrangement of PML bodies are influenced by A-type lamin deficiency. Biol Cell. 2012 Jul;104(7):418-32. doi: 10.1111/boc.201100053. Epub 2012 May 23.

61. Legartová S, Jugová A, Stixová L, Kozubek S, Fojtová M, Zdráhal Z, Lochmanová G, Bártová E. (2012) Epigenetic aspects of HP1 exchange kinetics in apoptotic chromatin. Biochimie. 2012 Sep 27. pii: S0300-9084(12)00387-2. doi: 10.1016/j.biochi.2012.09.027.

62. Šmigová J. Juda, Bártová E., Raška I. Dynamics of Polycomb chromatin domains under conditions of increased molecular crowding. Accepted in Biology of the Cell, 2013.

63. Legartová S., Stixová L., Strnad H., Kozubek S., Martinet N., Dekker FJ, Franek M., Bártová E. Basic nuclear processes affected by HAT and HDAC inhibitors. Epigenomics, 2013, 5(4):379-96.

64. Bártová E and Stixová L. Functional Consequences of Nuclear and Nucleolar Architecture. Kniha proteins of the Nucleolus, Editors: Danton H. O’Day and Andrew Catalano, Springer, 2013, ISBN 978-94-007-5818-6. doi: 10.1007/978-94-007-5818-6. Chapter in book.

65. Přikrylová T., Pacherník J., Kozubek S., Bártová E. Epigenetics and chromatin plasticity in embryonic stem cells. World Journal of Stem Cells, 5(3): 73-85. ISSN 1948-0210. doi: 10.4252/wjsc.v5.i3.73. review

66. Foltánková V, Legartová S, Kozubek S, Hofer M, Bártová E. DNA-damage response in chromatin of ribosomal genes and the surrounding genome. Gene. 2013, 15;522(2):156-67.

67. Foltánková V, Matula P, Sorokin D, Kozubek S, Bártová E. Hybrid detectors improved time-lapse confocal microscopy of PML and 53BP1 nuclear body colocalization in DNA lesions. Microsc Microanal. 2013, 19(2):360-9.

68. Juda P, Smigová J, Kováčik L, Bártová E, Raška I. Ultrastructure of cytoplasmic and nuclear inosine-5'-monophosphate dehydrogenase 2 "rods and rings" inclusions. J Histochem Cytochem. 2014 Oct;62(10):739-50.

69. Bártová E, Foltánková V, Legartová S, Sehnalová P, Sorokin DV, Suchánková J, Kozubek S.Coilin is rapidly recruited to UVA-induced DNA lesions and γ-radiation affects localized movement of Cajal bodies. Nucleus. 2014 May-Jun;5(3):460-8.

70. Krutá M, Seneklová M, Raška J, Salykin A, Zerzánková L, Pešl M, Bártová E, Franek M, Baumeisterová A, Košková S, Neelsen KJ, Hampl A, Dvořák P, Rotrekl V. Mutation Frequency Dynamics in HPRT Locus in Culture-Adapted Human Embryonic Stem Cells and Induced Pluripotent Stem Cells Correspond to Their Differentiated Counterparts. Stem Cells Dev. 2014 Oct 15;23(20):2443-54.

71. Legartová S, Kozubek S, Franek M, Zdráhal Z, Lochmanová G, Martinet N, Bártová E.Cell differentiation along multiple pathways accompanied by changes in histone acetylation status. Biochem Cell Biol. 2014 Apr;92(2):85-93.

72. Sehnalová P, Legartová S, Cmarko D, Kozubek S, Bártová E. Recruitment of HP1β to UVA-induced DNA lesions is independent of radiation-induced changes in A-type lamins. Biol Cell. 2014 May;106(5):151-65.

73. Legartová S, Stixová L, Laur O, Kozubek S, Sehnalová P, Bártová E. Nuclear structures surrounding internal lamin invaginations. J Cell Biochem. 2014 Mar;115(3):476-87.

74. Stixová L, Sehnalová P, Legartová S, Suchánková J, Hrušková T, Kozubek S, Sorokin DV, Matula P, Raška I, Kovařík A, Fulneček J, Bártová E. HP1β-dependent recruitment of UBF1 to irradiated chromatin occurs simultaneously with CPDs. Epigenetics Chromatin. 2014;7(1):39. doi:10.1186/1756-8935-7-39.

75. Stixová L, Hrušková T, Sehnalová P, Legartová S, Svidenská S, Kozubek S, Bártová E. Advanced microscopy techniques used for comparison of UVA- and γ-irradiation-induced DNA damage in the cell nucleus and nucleolus. Folia Biol (Praha). 2014;60 Suppl 1:76-84.

76. Sorokin DV, Suchánková J, Bártová E, Matula P. Visualizing stable features in live cell nucleus for evaluation of the cell global motion compensation. Folia Biol (Praha). 2014;60 Suppl 1:45-49.

77. Suchánková J, Legartová S, Sehnalová P, Kozubek S, Valente S, Labella D, Mai A, Eckerich C, Fackelmayer FO, Sorokin DV, Bártová E. PRMT1 arginine methyltransferase accumulates in cytoplasmic bodies that respond to selective inhibition and DNA damage. Eur J Histochem. 2014;58(2):2389. doi:10.4081/ejh.2014.2389.

78. Suchánková J, Kozubek S, Legartová S, Sehnalová P, Küntziger T, Bártová E. Distinct kinetics of DNA repair protein accumulation at DNA lesions and cell cycle-dependent formation of γH2AX- and NBS1-positive repair foci. Biol Cell. 2015. doi:10.1111/boc.201500050.

79. Sorokin D V, Stixová L, Sehnalová P, Legartová S, Suchánková J, Šimara P, Kozubek, Matula P, Skalníková M, Raška I, Bártová E. Localized movement and morphology of UBF1-positive nucleolar regions are changed by γ-irradiation in G2 phase of the cell cycle. Nucleus. 2015;6(4):301-313. doi:10.1080/19491034.2015.1075111.

80. Legartová S, Sbardella G, Kozubek S, Bártová E. Ellagic Acid-Changed Epigenome of Ribosomal Genes and Condensed RPA194-Positive Regions of Nucleoli in Tumour Cells. Folia Biol (Praha). 2015;61(2):49-59.

81. Franek M, Legartová S, Suchánková J, Milite C, Castellano S, Sbardella G, Kozubek S,  Bártová E. CARM1 modulators affect epigenome of stem cells and change morphology of nucleoli. Physiol Res. 2015.

82. Krejčí J, Stixová L, Pagáčová E, Legartová S, Kozubek S, Lochmanová G, Zdráhal Z, Sehnalová P, Dabrawolski S, Hejátko J, Bártová E. Post-Translational Modifications of Histones in Human Sperm. J Cell Biochem. 2015. doi:10.1002/jcb.25170.

83. Suchánková J, Kozubek S, Legartová S, Sehnalová P, Küntziger T, Bártová E. Distinct kinetics of DNA repair protein accumulation at DNA lesions and cell cycle-dependent formation of γH2AX- and NBS1-positive repair foci. Biol Cell. 2015. doi:10.1111/boc.201500050. IF=2.55*

84. Sorokin D V, Stixová L, Sehnalová P, Legartová S, Suchánková J, Šimara P, Kozubek, Matula P, Skalníková M, Raška I, Bártová E. Localized movement and morphology of UBF1-positive nucleolar regions are changed by γ-irradiation in G2 phase of the cell cycle. Nucleus. 2015;6(4):301-313. doi:10.1080/19491034.2015.1075111. IF=2.45*

85. Legartová S, Sbardella G, Kozubek S, Bártová E. Ellagic Acid-Changed Epigenome of Ribosomal Genes and Condensed RPA194-Positive Regions of Nucleoli in Tumour Cells. Folia Biol (Praha). 2015;61(2):49-59. IF=0.83*

86. Franek M, Legartová S, Suchánková J, Milite C, Castellano S, Sbardella G, Kozubek S,  Bártová E. CARM1 modulators affect epigenome of stem cells and change morphology of nucleoli. Physiol Res. 2015. IF=1.64*

87. Krejčí J, Stixová L, Pagáčová E, Legartová S, Kozubek S, Lochmanová G, Zdráhal Z, Sehnalová P, Dabrawolski S, Hejátko J, Bártová E. Post-Translational Modifications of Histones in Human Sperm. J Cell Biochem. 2015. doi:10.1002/jcb.25170.  IF=3.45*

88. Bártová E, Večeřa J, Krejčí J, Legartová S, Pacherník J, Kozubek S.The level and distribution pattern of HP1β in the embryonic brain correspond to those of H3K9me1/me2 but not of H3K9me3. Histochem Cell Biol. 2016. IF=2.78*

89. Franek M, Suchánková J, Sehnalová P, Krejčí J, Legartová S, Kozubek S, Večeřa J, Sorokin DV, Bártová E. Advanced Image Acquisition and Analytical Techniques for Studies of Living Cells and Tissue Sections. Microsc Microanal. 2016. IF=1.73*

90. Smirnov E, Hornáček M, Kováčik L, Mazel T, Schröfel A, Svidenská S, Skalníková M, Bartová E, Cmarko D, Raška I. Reproduction of the FC/DFC units in nucleoli. Nucleus. 2016;7(2):203-15. IF=2.45

91. Soňa Legartová, Petra Sehnalová, Barbora Malyšková, Thomas Küntziger, Philippe Collas, Dušan Cmarko, Ivan Raška, Dmitry V. Sorokin, Stanislav Kozubek and Eva Bártová. PML protein deficiency affects levels of 53BP1 protein and trajectory of 53BP1 positive DNA repair foci co-localizing with interchromatin granule-associated zones and nuclear speckles. Accepted for publication in Journal of Cellular Biochemistry, 2016; 117(11):2583-96. IF=3.45*

92. Legartová S, Sehnalová P, Malyšková B, Küntziger T, Collas P, Cmarko D, Raška I, Sorokin DV, Kozubek S, Bártová E. Cover Image, Volume 117, Number 11, November 2016. J Cell Biochem. 2016 Nov;117(11):i. doi: 10.1002/jcb.25671. IF=3.45*

93. Krejčí J, Legartová S, Bártová E. Neural Differentiation in HDAC1-Depleted Cells Is Accompanied by Coilin Downregulation and the Accumulation of Cajal Bodies in Nucleoli. Stem Cells Int. 2017;2017:1021240. doi: 10.1155/2017/1021240.

94. Bártová E, Malyšková B, Komůrková D, Legartová S, Suchánková J, Krejčí J, Kozubek S. Function of heterochromatin protein 1 during DNA repair. Protoplasma. 2017 May;254(3):1233-1240. doi: 10.1007/s00709-017-1090-3. Review.

95. Bártová E, Suchánková J, Legartová S, Malyšková B, Hornáček M, Skalníková M, Mašata M, Raška I, Kozubek S. PCNA is recruited to irradiated chromatin in late S-phase and is most pronounced in G2 phase of the cell cycle. Protoplasma. 2017 Jan 20. doi: 10.1007/s00709-017-1076-1.

96. Franek M, Kovaříková A, Bártová E, Kozubek S. Nucleolar Reorganization Upon Site-Specific Double-Strand Break Induction. J Histochem Cytochem. 2016 Nov;64(11):669-686. doi: 10.1369/0022155416668505.

97. Suchánková J, Legartová S, Ručková E, Vojtěšek B, Kozubek S, Bártová E.Mutations in the TP53 gene affected recruitment of 53BP1 protein to DNA lesions, but level of 53BP1 was stable after γ-irradiation that depleted MDC1 protein in specific TP53 mutants. Histochem Cell Biol. 2017 Apr 10. doi: 10.1007/s00418-017-1567-3.

98. Hornáček M, Kováčik L, Mazel T, Cmarko D, Bártová E, Raška I, Smirnov E. Fluctuations of pol I and fibrillarin contents of the nucleoli. Nucleus. 2017 Jun 16:1-12. doi: 10.1080/19491034.2017.1306160.

99. Legartová S, Suchánková J, Krejčí J, Kovaříková A, Bártová E. Advanced Confocal Microscopy Techniques to Study Protein-protein Interactions and Kinetics at DNA Lesions. J Vis Exp. 2017 Nov 12;(129). doi: 10.3791/55999.

100. Harikumar A, Edupuganti RR, Sorek M, Azad GK, Markoulaki S, Sehnalová P, Legartová S, Bártová E, Farkash-Amar S, Jaenisch R, Alon U, Meshorer E. An Endogenously Tagged Fluorescent Fusion Protein Library in Mouse Embryonic Stem Cells. Stem Cell Reports. 2017 Oct 10;9(4):1304-1314. doi: 10.1016/j.stemcr.2017.08.022. Epub 2017 Sep 28.

101. Bártová E, Lochmanová G, Legartová S, Suchánková J, Fedr R, Krejčí J, Zdráhal Z. Irradiation by γ-rays reduces the level of H3S10 phosphorylation and weakens the G2 phase-dependent interaction between H3S10 phosphorylation and γH2AX. Biochimie. 2018 Nov;154:86-98. doi: 10.1016/j.biochi.2018.07.029. Epub 2018 Aug 8.

102. Glazachev YI, Orlova DY, Řezníčková P, Bártová E. Effective scheme of photolysis of GFP in live cell as revealed with confocal fluorescence microscopy. Phys Biol. 2018 Mar 23;15(3):036008. doi: 10.1088/1478-3975/aab31e

103. Khalo IV, Konokhova AI, Orlova DY, Trusov KV, Yurkin MA, Bartova E, Kozubek S, Maltsev VP, Chernyshev AV. Nuclear apoptotic volume decrease in individual cells: Confocal microscopy imaging and kinetic modeling J Theor Biol. 2018 Oct 7;454:60-69. doi: 10.1016/j.jtbi.2018.05.034.

104. Eva Bártová, Soňa Legartová, Jana Krejčí, Petra Řezníčková, Alena Kovaříková, Jana Suchánková, Radek Fedr, Evgeny Smirnov, Matúš Hornáček and Ivan Raška.  Depletion of A-type lamins and Lap2 reduces 53BP1 accumulation at UV-induced DNA lesions and Lap2 protein is responsible for compactness of irradiated chromatin. Accepted for publication in J Cell Biochem. 2018.

105. Svobodová Kovaříková A, Legartová S, Krejčí J, Bártová E. H3K9me3 and H4K20me3 represent the epigenetic landscape for 53BP1 binding to DNA lesions. Aging (Albany NY). 2018 Oct 11;10(10):2585-2605. doi: 10.18632/aging.101572.

106. Arcidiacono OA, Krejčí J, Suchánková J, Bártová E. Deacetylation of Histone H4 Accompanying Cardiomyogenesis is Weakened in HDAC1-Depleted ES Cells. Int J Mol Sci. 2018 Aug 16;19(8). pii: E2425. doi: 10.3390/ijms19082425.

107. Večeřa J, Bártová E, Krejčí J, Legartová S, Komůrková D, Rudá-Kučerová J, Štark T, Dražanová E, Kašpárek T, Šulcová A, Dekker FJ, Szymanski W, Seiser C, Weitzer G, Mechoulam R, Micale V, Kozubek S. HDAC1 and HDAC3 underlie dynamic H3K9 acetylation during embryonic neurogenesis and in schizophrenia-like animals. J Cell Physiol. 2018 Mar 16.

108. Pokorná P, Krepl M, Bártová E, Šponer J. Role of Fine Structural Dynamics in Recognition of Histone H3 by HP1γ(CSD) Dimer and Ability of Force Fields to Describe Their Interaction Network. J Chem Theory Comput. 2019 Oct 8;15(10):5659-5673. doi: 10.1021/acs.jctc.9b00434. Epub 2019 Sep 18.

109. Bártová E, Legartová S, Dundr M, Suchánková J.A role of the 53BP1 protein in genome protection: structural and functional characteristics of 53BP1-dependent DNA repair. Aging (Albany NY). 2019 Apr 17;11(8):2488-2511. doi: 10.18632/aging.101917.

110. Stixová L, Komůrková D, Svobodová Kovaříková A, Bártová E. UVA irradiation strengthened an interaction between UBF1/2 proteins and H4K20 di-/tri-methylation. Chromosome Res. 2019 Mar;27(1-2):41-55. doi: 10.1007/s10577-018-9596-x. Epub 2019 Jan

111. Legartová S, Lochmanová G, Zdráhal Z, Kozubek S, Šponer J, Krepl M, Pokorná P, Bártová E. DNA Damage Changes Distribution Pattern and Levels of HP1 Protein Isoforms in the Nucleolus and Increases Phosphorylation of HP1β-Ser88. Cells. 2019 Sep 17;8(9). pii: E1097. doi: 10.3390/cells8091097.

113. Svobodová Kovaříková A, Stixová L, Kovařík A, Komůrková D, Legartová S, Fagherazzi P, Bártová E. N6-Adenosine Methylation in RNA and a Reduced m3G/TMG Level in Non-Coding RNAs Appear at Microirradiation-Induced DNA Lesions. Cells. 2020 Feb 4;9(2). pii: E360. doi: 10.3390/cells9020360. 

112.  E Bártová, S Legartová,J Krejčí,OA Arcidiacono. Cell differentiation and aging accompanied by depletion of ACE2. Aging (Albany NY) 12 (22), 22495, 2020

114. A Svobodová Kovaříková, E Bártová, A Kovařík, E Lukášová. Spatiotemporal mislocalization of nuclear membrane-associated proteins in γ-irradiation-induced senescent cells. Cells 9 (4), 999, 2020                     

115. OA Arcidiacono, J Krejčí, E Bártová. The distinct function and localization of METTL3/METTL14 and METTL16 enzymes in cardiomyocytes. International Journal of Molecular Sciences 21 (21), 8139, 2020.

116. OA Arcidiacono, J Krejčí, S Legartová, L Stixova, E Bártová. Epigenetic processes and DNA repair in embryonic stem cells.  Stem Cell Epigenetics, 1-23, A book Chapter, 2020.

117. Legartova S., J Suchankova, E Bartova. PARP dependent recruitment of RNA methylated at 8-adenosine is linked to base excision repair mechanism. Preprint Research Square, 2021.

118.  Legartová, P Fagherazzi, L Stixová, A Kovařík, I Raška, E Bártová. The SC-35 Splicing Factor Interacts with RNA Pol II and A-Type Lamin Depletion Weakens This Interaction. Cells 10 (2), 297, 2021.                             

119. Komůrková, AS Kovaříková, E Bártová. G Quadruplex Structures Colocalize with Transcription  Factories and Nuclear Speckles Surrounded by Acetylated and Dimethylated Histones H3. International Journal of Molecular Sciences 22 (4), 2021

120. Stixová L, Komůrková D, Svobodová Kovaříková A, Fagherazzi P, Bártová E. Localization of METTL16 at the Nuclear Periphery and the Nucleolus Is Cell Cycle-Specific and METTL16 Interacts with Several Nucleolar Proteins.  Life (Basel). 2021 Jul 8;11(7):669. doi: 10.3390/life11070669.

121. Legartová S, Svobodová Kovaříková A, Běhalová Suchánková J, Polášek-Sedláčková H, Bártová E. Early recruitment of PARP-dependent m8A RNA methylation at DNA lesions is subsequently accompanied by active DNA demethylation. RNA Biol. 2022 Jan;19(1):1153-1171. doi: 10.1080/15476286.2022.2139109.

122. Legartová S, Lochmanová G, Bártová E. The Highest Density of Phosphorylated Histone H1 Appeared in Prophase and Prometaphase in Parallel with Reduced H3K9me3, and HDAC1 Depletion Increased H1.2/H1.3 and H1.4 Serine 38 Phosphorylation.  Life (Basel). 2022 May 27;12(6):798. doi: 10.3390/life12060798.

123. Legartová S, Fagherazzi P, Goswami P, Brazda V, Lochmanová G, Koutná I, Bártová E. Irradiation potentiates p53 phosphorylation and p53 binding to the promoter and coding region of the TP53 gene.  Biochimie. 2023 Jan;204:154-168. doi: 10.1016/j.biochi.2022.09.013. Epub 2022 Sep 24.

124. Svobodová Kovaříková A, Stixová L, Kovařík A, Bártová E. PARP-dependent and NAT10-independent acetylation of N4-cytidine in RNA appears in UV-damaged chromatin. Epigenetics Chromatin. 2023 Jun 15;16(1):26. doi: 10.1186/s13072-023-00501-x.

125. Krejčí J, Arcidiacono OA, Čegan R, Radaszkiewicz K, Pacherník J, Pirk J, Pešl M, Fila P, Bártová E. Cell Differentiation and Aging Lead To Up-Regulation of FTO, While the ALKBH5 Protein Level Was Stable During Aging but Up-Regulated During in vitro-Induced Cardiomyogenesis. Physiol Res. 2023 Aug 31;72(4):425-444. doi: 10.33549/physiolres.935078.

126. Stixová L, Tichý V, Bártová E. RNA-related DNA damage and repair: The role of N7-methylguanosine in the cell nucleus exposed to UV light.  Heliyon. 2024 Feb 7;10(4):e25599. doi: 10.1016/j.heliyon.2024.e25599.  eCollection 2024 Feb 29.

127. Kovaříková AS, Stixová L, Kovařík A, Komůrková D, Legartová S, Fagherazzi P, Bártová E. Correction: Svobodova et al. N6-Adenosine Methylation in RNA and a Reduced m3G/TMG Level in Non-Coding RNAs Appear at Microirradiation-Induced DNA Lesions. Cells 2020, 9, 360.

128. Bártová E. Epigenetic and gene therapy in human and veterinary medicine. Environ Epigenet. 2024 May 10;10(1):dvae006. doi: 10.1093/eep/dvae006. eCollection 2024.

129. Bártová E, Stixová L, Svobodová Kovaříková A. N4-acetylcytidine and other RNA modifications in epitranscriptome: insight into DNA repair and cancer development.  Epigenomics. 2025 Apr;17(6):411-422. doi: 10.1080/17501911.2025.2473308.

130. Kovařík A, Hof M, Bártová E. European Biophysics Journal - Special Issue Celebrating the 70th Anniversary of the Institute of Biophysics, Czech Academy of Sciences.  Eur Biophys J. 2025 Nov;54(8):527-528. doi: 10.1007/s00249-025-01804-5. 

131. Bártová E, Kozubek S, Kovařík A. Biophysics in the Czech Republic: 70th anniversary of the Institute of Biophysics.  Eur Biophys J. 2025 Nov;54(8):529-535. doi: 10.1007/s00249-025-01795-3. Epub 2025 Sep 28. PMID: 41015982 Free PMC article. Review.

132. Fagherazzi P, Stixová L, Bartova E. Specific TP53 mutations impair the recruitment of 53BP1 to DNA double-strand breaks underlying the mechanism of radioresistance.  Eur Biophys J. 2025 Nov;54)8):601-612. doi: 10.1007/s00249-025-01774-8. Epub 2025 Jul 14. PMID: 40659933.