Mlýnský Vojtěch, Mgr., Ph.D.

Extension: +420 541-517- 277

Research Interests

  • Molecular dynamics of RNA and RNA:protein complexes
  • Interactions of RNA with small molecules
  • Enhanced Sampling Methods and their application to RNA dynamics
  • QM and QM/MM calculations of RNA catalytic reactions


  • 2005 – 2009 - M.Sc. Physical Chemistry, Palacký University, Olomouc
  • 2009 – 2014 - Ph.D. Physical chemistry, Palacký University, Olomouc

International Experience

  • 2012 - Stay at University of Bristol (group of Prof. Adrian J. Mulholland)
  • 2013 - Stay at University of Michigan (group of Prof. Nils G. Walter)
  • 2015 – 2018 - Postdoc at SISSA, Trieste, Italy (group of Prof. Giovanni Bussi)


  • Prof. Giovanni Bussi, SISSA, Trieste, Italy – Enhanced Sampling Methods 

Recent Publications

Mlynsky V, Bussi G: Exploring RNA structure and dynamics through enhanced sampling simulations, CURR. OPIN. STRUCT. BIOL., in press (2018)

Mlynsky V, Bussi G: Molecular Dynamics Simulations Reveal an Interplay between SHAPE Reagent Binding and RNA Flexibility, J. PHYS. CHEM. LETT., 9(2), 313-318 (2018)

Mlynsky V, Kuhrova P, Jurecka P, Sponer J, Otyepka M, Banas P: Mapping the Chemical Space of the RNA Cleavage and its Implications for Ribozyme Catalysis, J. PHYS. CHEM. B, 121(48), 10828-10840 (2017)

Mlynsky V, Bussi G: Understanding in-line probing experiments by modeling cleavage of nonreactive RNA nucleotides, RNA, 23(5), 712-720 (2017)