Semester courses of DCBE

The most important projects and collaboration of DCBE with universities

1. LC535, Center of Basic Research: Structure of the cell nucleus in normal and pathological conditions, coordinator I. Raška, investigator, S. Kozubek (IBP AS CR), Kyra Michalova (FM UK), Michal Kozubek (FI MU), 2 joint publications
2. LC06027, Center of Basic Research: Monoclonal gammopathy and multiple myeloma, coordinator R. Hájek, investigator E. Bártová (IBP AS CR)
3. Other collaboration: P. Matula, analysis of confocal images (5 joint publications)

Graduate students educated in the Department of Cell Biology and Epigenetics

thesis supervisor (S); Mgr. = MSc.; Bc. = BSc.

Paolo Fagherazzi

PhD (running): Role of p53 in the early phase DNA repair: Mechanism and its correlation with the function of the 53BP1 protein (S: assoc. prof. RNDr. Eva Bártová, PhD, DSc)

Ľubomír Habaň

Mgr. (2023): Study of lamin proteins in DNA damage repair (S: assoc. prof. RNDr. Eva Bártová, PhD, DSc)

Veronika Knechtová

Mgr. (2022): Changes in the histone code caused by mutation in the TP53 gene (S: Mgr. Soňa Legartová, PhD)

Orazio A. Arcidiacono

PhD (2022): Epigenetics features of mouse embryonic stem cells differentiation into cardiomyocytes (S: assoc. prof. RNDr. Eva Bártová, PhD, DSc)

Alena Svobodová Kovaříková

PhD (2019): Epigenetic Processes during DNA repair (S: assoc. prof. RNDr. Eva Bártová, PhD, DSc)

Jana Suchánková

PhD (2018): DNA repair mechanism studied by advanced confocal microscopy (S: assoc. prof. RNDr. Eva Bártová, PhD, DSc)

Mgr. (2013): DNA repair and epigenetics processes (S: assoc. prof. RNDr. Eva Bártová, PhD, DSc)

Bc. (2011): Epigenetics of nucleolus (S: assoc. prof. RNDr. Eva Bártová, PhD, DSc)

Iveta Vavříková

Mgr. (2017): Studies on protein interaction by FLIM-FRET and confocal microscopy (S: assoc. prof. RNDr. Eva Bártová, PhD, DSc)

Petra Lesáková

Bc. (2017): Chromatin structure in normal and pathology cell (S: assoc. prof. RNDr. Eva Bártová, PhD, DSc)

Michal Franek

PhD (2017): Study of nucleolar reorganization in embryonic stem cells (S: assoc. prof. RNDr. Eva Bártová, PhD, DSc) 

Mgr. (2014): Dynamic plasticity of epigenetic proteins in embrynic stem cells (S: assoc. prof. RNDr. Eva Bártová, PhD, DSc)

Bc. (2012): Functional significance of histone signature (S: assoc. prof. RNDr. Eva Bártová, PhD, DSc)

Petra Sehnalová

PhD (2017): How to use an advanced confocal microscopy and FRAP analysis for study of chromatin structure and dynamics (S: assoc. prof. RNDr. Eva Bártová, PhD, DSc)

Mgr. (2012): Study on protein dynamic in embryonal stem cells by the use of FRAP technique (S: assoc. prof. RNDr. Eva Bártová, PhD, DSc)

Bc. (2010): Chromatin structure and its dynamics studies by FRAP technique (S: assoc. prof. RNDr. Eva Bártová, PhD, DSc)

Barbora Malyšková

Mgr. (2016): Morphology of nuclear lamina and function of nuclear lamins during DNA repair (S: assoc. prof. RNDr. Eva Bártová, PhD, DSc)

Bc. (2014): FRAP technique and its application in living cell studies (S: assoc. prof. RNDr. Eva Bártová, PhD, DSc)

Martina Nemčeková

Mgr. (2016): Epigenetics of mouse embryonic stem cells during neural differentiation (S: Mgr. Jana Krejčí, PhD)

Bc. (2013): Comparison of physiology and epigenetics of embryonic stem cells and induced pluripotent cells (S: assoc. prof. RNDr. Eva Bártová, PhD, DSc)

Tereza Hrušková

Mgr. (2015): The role of Oct4 protein in DNA damage response in embryonal stem cells (S: Mgr. Lenka Stixová, PhD)

Bc. (2013): DNA repair and epigenetic processes in embryonic stem cells (S: assoc. prof. RNDr. Eva Bártová, PhD, DSc)

Terézia Přikrylová

Mgr. (2014): Cell cycle-dependent nuclear pattern of chromatin-associated proteins (S: assoc. prof. RNDr. Eva Bártová, PhD, DSc)

Bc. (2012): Chromatin plasticity and epigenetics in embrynic stem cells (S: assoc. prof. RNDr. Eva Bártová, PhD, DSc)

Daniel Depeš

Bc. (2014): Epigenetic features of apoptotic cells (S: assoc. prof. RNDr. Eva Bártová, PhD, DSc)

Markéta Hájková

Bc. (2012): Study on epigenetic changes in human embrynic stem cells (S: assoc. prof. RNDr. Eva Bártová, PhD, DSc)

Darya Y. Orlova

PhD. (2012): Distribution function approach to kinetic study of ligand-receptor interactions by flow cytometry and confocal laser scanning microscopy (S: assoc. prof. RNDr. Stanislav Kozubek, DrSc.)

Veronika Foltánková

PhD (2012): Specific immunologic and epigenetic properties of the tumour cells and their importance in the therapy of selected haematological malignancies (S: prof. MUDr. Roman Hájek, CSc.)

• part results of the PhD thesis was done under a supervsion of Eva Bártová at Institue of Biophysics fo Czech Academy of Sciences and published in three peer-reviewd papers: Foltánková et al. (2012),  Foltánková et al. 2013a and Foltánková et al. 2013b

Radka Uhlířová

Mgr. (2010): Functional and structural importance of PML bodies and their relationship to telomeric heterochromatin (S: assoc. prof. RNDr. Eva Bártová, PhD, DSc)

Bc. (2008): Nuclear organization of promyelocytic leukaemia bodies in myeloma and leukemic cells (S: assoc. prof. RNDr. Eva Bártová, PhD, DSc)

Alžběta Jugová

Mgr. (2012): Study on epigenetic changes in leukemic cells and cells of multiple myeloma (S: assoc. prof. RNDr. Eva Bártová, PhD, DSc)

Bc. (2009): The effects of HDACs and Dnmts inhibitors on chromatin structure and function (S: assoc. prof. RNDr. Eva Bártová, PhD, DSc)

Soňa Legartová

PhD (2014): Structure and selected functions of chromatin as a markers for clinical diagnostics (S: assoc. prof. RNDr. Stanislav Kozubek, DrSc.)

Mgr. (2008): Nuclear topography of chromosome territory HSA1 and genomic locus 1q21 in multiple myeloma cells using high-resolution confocal microscopy (S: Mgr. Jana Krejčí, PhD)

Eva Slavíčková

Bc. (2009): Fragile sites in human genome (S: Mgr. Pavla Gajdúšková, Ph.D.)

Gabriela Galiová-Šustáčková

PhD (2009): Spatial nuclear arrangement of the genome in humans, higher primates and another animal species (S: assoc. prof. RNDr. Stanislav Kozubek, DrSc.)

Mgr. (2004): Isolation of DNA DNA from PAC and BAC clones of Escherichia coli and its use in gene visualization by Fluorescence In Situ Hybridization method

Andrea Harničarová-Horáková

PhD (2008): Nuclear topography and transcriptional activity of the c-myc gene during enterocytic differentiation (S: assoc. prof. RNDr. Stanislav Kozubek, DrSc.)

Kateřina Buchníčková