Biophysics of Immune System

Finished projects

Novel organic semiconductors for future bioelectronics devices for regenerative medicine

Project ID code: 21-01057S
Provider: GAČR
Years: 2021 - 2023
Solver: Jan Víteček
The goal of the project is proposal and optimization of novel organic semiconductors, advanced studies of electron and ion processes and interactions of the materials with living cells, resulting in proposal of novel bioelectronic device for effective electrical stimulation of endothelial cells.

Targeted polymer therapeutics for advanced treatment of site-specific rheumatic musculoskeletal diseases

Project ID code: NU20-08-00255
Provider: Ministerstvo zdravotnictví
Years: 2020 - 2023
Solver: Lukáš Kubala

Application of hyaluronic acid nanofibers in cosmetics and medicine

Project ID code: CZ.01.1.02/0.0/0.0/17_176/0015514
Provider: MPO - Operační program Podnikání a inovace pro konkurenceschopnost / Ministry of trade - Operational Programme Enterprise and Innovations for Competitiveness
Years: 2020 - 2022
Solver: Lukáš Kubala, Gabriela Ambrožová, Kristina Turková

Pro-inflammatory effects of LPS of cyanobacterial water bloom from freshwater reservoirs in the Czech Republic

Project ID code: 19-09980S
Provider: GAČR
Years: 2019 - 2021

Novel nature-inspired organic semiconductors for bioelectronics

Project ID code: 17-24707S
Provider: GAČR
Years: 2017 - 2019
Solver: Jan Víteček

Natural pseurotin alkaloids as significant immunotoxic contaminants

Project ID code: 17-18858S
Provider: GAČR
Years: 2017 - 2019
Solver: Lukáš Kubala

A complex role of nitro-fatty acids in regulation of cellular functions and processes: beyond the anti-inflammatory effect

Project ID code: 17-08066Y
Provider: GAČR
Years: 2017 - 2019
Solver: Michaela Pekarová

Importance of Toll-like receptors in intestinal epithelium response to cyanobacterial water bloom

Project ID code: 16-24949S
Provider: GAČR
Years: 2016 - 2018
Solver: Lenka Švihálková Šindlerová

Molecular mechanisms of serotoninergic system interactions with cells of immune system

Project ID code: LD14030
Provider: MŠMT
Years: 2014 - 2016
Solver: Číž, M.

Materials for integration of animal cells with organic electronics: towards future bioelectronic devices

Project ID code: 13-29358S
Provider: GAČR
Years: 2013 - 2016
Solver: Víteček, J. (spoluřešitel)

New Role for Nitrated Fatty Acid in Modulation of Phagocyte-derived Inflammatory Responses

Project ID code: 13-40824P
Provider: GA ČR
Years: 2013 - 2015
Solver: Ambrožová, G.

Role of L-arginine, methylarginines and their metabolism in regulation of endothelial homeostasis

Project ID code: 13-40882P
Provider: GAČR
Years: 2013 - 2014
Solver: Pekarová, M.

Importance of the interaction of myeloperoxidase with the endothelial glycocalyx for leukocyte recruitment and vascular fuction

Project ID code: P305/12/J038
Provider: GA ČR
Years: 2012 - 2014
Solver: Kubala, L.

The influence of L-arginine and its analogues on the generation of reactive oxygen and nitrogen species by professional phagocytes

Project ID code: 524/08/1753
Provider: GA ČR
Years: 2008 - 2012
Solver: Lojek, A

Role extracelulárního L-argininu v regulaci produkce oxidu dusnatého u endoteliálních buněk

Provider: Jihomoravské centrum pro mezinárodní mobilitu
Years: 2011 - 2011
Solver: Pekarová, M.

Interactions among collagen, platelets and phagocytes in modulation of reactive oxygen and nitrogen species production

Project ID code: OC10044
Provider: MŠMT
Years: 2010 - 2011
Solver: Číž, M.

Effect of polyunsaturated fatty acids and their metabolites on the physiological functions of professional phagocytes

Project ID code: OC08058
Provider: MŠMT
Years: 2008 - 2010
Solver: Lojek, A.

Role of hyaluronan of different molecular weight in the course of inflammation

Project ID code: 305/08/1704
Provider: GA ČR
Years: 2008 - 2010
Solver: Kubala, L.

Úloha krevních destiček, neutrofilů a složek mezibuněčné hmoty v zánětu. Analýza léčiv a perspektivních přírodních látek.

Project ID code: MEB0808106
Provider: MŠMT
Years: 2008 - 2009

Collagen, platelet and neutrophil interactions with respect to wound healing

Project ID code: 524/07/1511
Provider: GA ČR
Years: 2007 - 2009
Solver: Číž, M.

The role of uric acid in endothelial dysfunction

Project ID code: 204/07/P539
Provider: GA ČR
Years: 2007 - 2009
Solver: Papežíková, I.

The use of terestric bioluminescent bacteria in ecotoxicology

Project ID code: 525/06/1196
Provider: GA ČR
Years: 2006 - 2008
Solver: Lojek, A.

The role of free radicals in regulation of lung inflammation induced by acute or chronic exposition to endotoxin

Project ID code: 524/06/1197
Provider: GA ČR
Years: 2006 - 2008
Solver: Kubala, L.

Effects of carvedilol on metabolic activity of neutrophils and monocytes

Project ID code: 305/04/0896
Provider: GA ČR
Years: 2004 - 2006
Solver: Lojek, A.

The role of serotonin in mutual interactions of platelets and professional phagocytes

Project ID code: 524/04/0897
Provider: GA ČR
Years: 2004 - 2006
Solver: Číž, M.

The influence of hyaluronic acid on the functions and interactions of leukocytes and epithelial cells under physiological and inflammatory conditions

Project ID code: 524/02/0395
Provider: GA ČR
Years: 2002 - 2004
Solver: Lojek, A.

Antioxidative properties of flavonoids with respect to the oxidative burst of phagocyte and cooperation between phagocytes and endothelial cells

Project ID code: B6004204
Provider: GA AS ČR
Years: 2002 - 2004
Solver: Číž, M.

Understanding and modulation of the antioxidative defence mechanisms in oxidative stress

Project ID code: 524/01/1219
Provider: GA ČR
Years: 2001 - 2003
Solver: Číž, M.

Reactive oxygen and nitrogen metabolites generated by neutrophils under physiological and pathophysiological conditions

Project ID code: 524/00/1223
Provider: GA ČR
Years: 2000 - 2002
Solver: Lojek, A.

Influence of different time of ischemia adn reperfusion upon development of reperfusion injury intestine

Project ID code: 524/99/D022
Provider: GA ČR
Years: 1999 - 2002
Solver: Čížová, H.

The role of endogenous antioxidants in the regulation of post-ischemic oxidative stress

Project ID code: 524/98/0190
Provider: GA ČR
Years: 1998 - 2000
Solver: Číž, M.

Reactive oxygen species in relation to hemodialysis and kidney transplantation

Project ID code: 4796-3
Provider: IGA MZ ČR
Years: 1998 - 2000
Solver: Číž, M., Lojek, A.

The role of oxygen metabolites and nitric oxide in the development of intestinal reperfusion injury

Project ID code: 308/97/1141
Provider: GA ČR
Years: 1997 - 1999
Solver: Lojek, A.

Mechanisms of transplanted tissue injuries during their ischemia and reperfusion and prevention prospects

Project ID code: 2849-3
Provider: IGA MZ ČR
Years: 1995 - 1997
Solver: Číž, M., Lojek, A.

The role of oxygen free radicals in the hypoxic and reperfused tissues

Project ID code: 308/94/0387
Provider: GA ČR
Years: 1994 - 1996
Solver: Lojek, A.