G4Hunter web application: a web server for G-quadruplex prediction

Abstract

Motivation: Expanding research highlights the importance of guanine quadruplex structures. Therefore, easy-accessible tools for quadruplex analyses in DNA and RNA molecules are important for the scientific community. Results: We developed a web version of the G4Hunter application. This new web-based server is a platform-independent and user-friendly application for quadruplex analyses. It allows retrieval of gene/nucleotide sequence entries from NCBI databases and provides complete characterization of localization and quadruplex propensity of quadruplex-forming sequences. The G4Hunter web ap- plication includes an interactive graphical data representation with many useful options including visualization, sorting, data storage and export. Availability and implementation: G4Hunter web application can be accessed at: http://bioinformat ics.ibp.cz. Contact: vaclav@ibp.cz