Institute of Biophysics

14.12. -

02.07. -

Thermodynamic and Mechanistic Insights into Translesion DNA Synthesis Catalyzed by Y-Family DNA Polymerase Across a Bulky Double-Base Lesion of an Antitumor Platinum Drug

The Role of Adenosine Receptor Agonists in Regulation of Hematopoiesis

Different Features of the DNA Binding Mode of Antitumor cis-Amminedichlorido(cyclohexylamine)platinum(H) (JM118) and Cisplatin in Vitro

Unfolding/denaturation and aggregation of proteins viewed by electrochemical methods

Pioneering work of the group headed by prof. E. Paleček in the field of electrochemical analysis of proteins based on their electrocatalytic activity giving rise to “peak H”.

Detecting DNA damage and monitoring of enzymatic DNA processing by electrochemical methods

Electrochemical approaches have been applied to detect specific nucleobase lesions and to design fast techniques for the monitoring of DNA-processing enzymes activity.

Electroactive labeling of DNA and PNA by osmium tetroxide complexes

The labeling reaction can be performed in any biochemical or biological laboratory without any special requirements for equipment or expertise.

AVČR - Akademie věd České republiky
MU - Masarykova univerzita, Brno
VUT - Vysoké učení technické, Brno
UK - Karlova univerzita, Praha

GA ČR - Grantová agentura ČR
GA AV - Interní grantová agentura AV ČR

CEITEC - Středoevropský technologický institut
OPVK - Strukturální fondy EU
FNUSA-ICRC - Mezinárodní centrum klinického výzkumu