Selected results

Detecting DNA damage and monitoring of enzymatic DNA processing by electrochemical methods

Electrochemical approaches have been applied to detect specific nucleobase lesions and to design fast techniques for the monitoring of DNA-processing enzymes activity.

Electroactive labeling of DNA and PNA by osmium tetroxide complexes

The labeling reaction can be performed in any biochemical or biological laboratory without any special requirements for equipment or expertise.

Osmium tetroxide, 2,2'-bipyridine (Os,bipy): Electroactive marker for probing accessibility of tryptophan residues in proteins.

Os,bipy forms at physiological conditions electroactive covalent adducts with tryptophan residues. 

Further results