Publications Overview of the Department of Molecular Biophysics and Pharmacology

2013

• Pracharova, J., Novakova, O., Kasparkova, J., Gibson, D., Brabec, V. (2013), Toxicity in tumor cells, DNA binding mode, and resistance to decomposition by sulfur nucleophiles of new dinuclear bifunctional trans-Pt-II complexes containing long alkane linkers, PURE AND APPLIED CHEMISTRY 85, 343-354 [AIS=0.918, IF=2.789 VH]

2012

• Terenzi, A., Ducani, C., Blanco, V., Zerzankova, L., Westendorf, AF., Peinador, C., Quintela, JM., Bednarski, PJ., Barone, G., Hannon, MJ. (2012), DNA Binding Studies and Cytotoxicity of a Dinuclear PtII Diazapyrenium-Based Metallo-supramolecular Rectangular Box, CHEMISTRY-A EUROPEAN JOURNAL 18, 10983-10990 [AIS=1.532, IF=5.925 H]
• Florian, J., Brabec, V. (2012), Thermodynamics of Translesion Synthesis across a Major DNA Adduct of Antitumor Oxaliplatin: Differential Scanning Calorimetric Study, CHEMISTRY-A EUROPEAN JOURNAL 18, 1634-1639 [AIS=1.527, IF=5.925 VH]
• Tai, HC., Brodbeck, R., Kasparkova, J., Farrer, NJ., Brabec, V., Sadler, PJ., Deeth, RJ. (2012), Combined Theoretical and Computational Study of Interstrand DNA Guanine-Guanine Cross-Linking by trans-[Pt(pyridine)(2)] Derived from the Photoactivated Prodrug trans,trans,trans-[Pt(N-3)(2)(OH)(2)(pyridine)(2)], INORGANIC CHEMISTRY 51, 6830-6841 [AIS=0.964, IF=4.601 H]
• Betanzos-Lara, S., Salassa, L., Habtemariam, A., Novakova, O., Pizarro, AM., Clarkson, GJ., Liskova, B., Brabec, V., Sadler, PJ. (2012), Photoactivatable Organometallic Pyridyl Ruthenium(II) Arene Complexes, ORGANOMETALLICS 31, 3466-3479 [AIS=0.83, IF=3.963 H]
• Starha, P., Travnicek, Z., Popa, A., Popa, I., Muchova, T., Brabec, V. (2012), How to modify 7-azaindole to form cytotoxic Pt(II) complexes: Highly in vitro anticancer effective cisplatin derivatives involving halogeno-substituted 7-azaindole, JOURNAL OF INORGANIC BIOCHEMISTRY 115, 57-63 [AIS=0.792, IF=3.354 H]
• Plsikova, J., Janovec, L., Koval, J., Ungvarsky, J., Mikes, J., Jendzelovsky, R., Fedorocko, P., Imrich, J., Kristian, P., Kasparkova, J., Brabec, V., Kozurkova, M. (2012), 3,6-Bis(3-alkylguanidino)acridines as DNA-intercalating antitumor agents, EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY 57, 283-295 [AIS=0.707, IF=3.346 H]
• Betanzos-Lara, S., Novakova, O., Deeth, RJ., Pizarro, AM., Clarkson, GJ., Liskova, B., Brabec, V., Sadler, PJ., Habtemariam, A. (2012), Bipyrimidine ruthenium(II) arene complexes: structure, reactivity and cytotoxicity, JOURNAL OF BIOLOGICAL INORGANIC CHEMISTRY 17, 1033-1051 [AIS=1.029, IF=3.289 H]
• Muchova, T., Quintal, SM., Farrell, NP., Brabec, V., Kasparkova, J. (2012), Antitumor bifunctional dinuclear Pt-II complex BBR3535 forms interduplex DNA cross-links under molecular crowding conditions, JOURNAL OF BIOLOGICAL INORGANIC CHEMISTRY 17, 239-245 [AIS=0, IF=0 H]
• Howson, SE., Bolhuis, A., Brabec, V., Clarkson, GJ., Malina, J., Rodger, A., Scott, P. (2012), Optically pure, water-stable metallo-helical 'flexicate' assemblies with antibiotic activity, NATURE CHEMISTRY 4, 31-36 [AIS=8.167, IF=17.927 H]
• Brabec, V., Malina, J., Margiotta, N., Natile, G., Kasparkova, J. (2012), Thermodynamic and Mechanistic Insights into Translesion DNA Synthesis Catalyzed by Y-Family DNA Polymerase Across a Bulky Double-Base Lesion of an Antitumor Platinum Drug, CHEMISTRY-A EUROPEAN JOURNAL 18, 15439-15448 [AIS=1.532, IF=5.925 VH]
• Mlcouskova, J., Malina, J., Novohradsky, V., Kasparkova, J., Komeda, S., Brabec, V. (2012), Energetics, conformation, and recognition of DNA duplexes containing a major adduct of an anticancer azolato-bridged dinuclear Pt-II complex, BIOCHIMICA ET BIOPHYSICA ACTA-GENERAL SUBJECTS 1820, 1502-1511 [AIS=1.194, IF=5 VH]
• Brabec, V., Griffith, DM., Kisova, A., Kostrhunova, H., Zerzankova, L., Marmion, CJ., Kasparkova, J. (2012), Valuable Insight into the Anticancer Activity of the Platinum-Histone Deacetylase Inhibitor Conjugate, cis-[Pt(NH3)(2)malSAHA_(2H))], MOLECULAR PHARMACEUTICS 9, 1990-1999 [AIS=1.52, IF=4.782 VH]
• Malina, J., Novakova, O., Natile, G., Brabec, V. (2012), The Thermodynamics of Translesion DNA Synthesis Past Major Adducts of Enantiomeric Analogues of Antitumor Cisplatin, CHEMISTRY-AN ASIAN JOURNAL 7, 1026-1031 [AIS=1.248, IF=4.5 VH]
• Cegan, R., Vyskot, B., Kejnovsky, E., Kubat, Z., Blavet, H., Safar, J., Dolezel, J., Blavet, N., Hobza, R. (2012), Genomic Diversity in Two Related Plant Species with and without Sex Chromosomes - Silene latifolia and S. vulgaris, PLOS ONE 7 [AIS=1.797, IF=4.092 V]
• Liskova, B., Zerzankova, L., Novakova, O., Kostrhunova, H., Travnicek, Z., Brabec, V. (2012), Cellular Response to Antitumor cis-Dichlorido Platinum(II) Complexes of CDK Inhibitor Bohemine and Its Analogues, CHEMICAL RESEARCH IN TOXICOLOGY 25, 500-509 [AIS=1.043, IF=3.779 VH]
• Pracharova, J., Zerzankova, L., Stepankova, J., Novakova, O., Farrer, NJ., Sadler, PJ., Brabec, V., Kasparkova, J. (2012), Interactions of DNA with a New Platinum(IV) Azide Dipyridine Complex Activated by UVA and Visible Light: Relationship to Toxicity in Tumor Cells, CHEMICAL RESEARCH IN TOXICOLOGY 25, 1099-1111 [AIS=1.039, IF=3.779 VH]
• Mlcouskova, J., Kasparkova, J., Suchankova, T., Komeda, S., Brabec, V. (2012), DNA conformation and repair of polymeric natural DNA damaged by antitumor azolato-bridged dinuclear Pt-II complex, JOURNAL OF INORGANIC BIOCHEMISTRY 114, 15-23 [AIS=0.792, IF=3.354 VH]
• Mlcouskova, J., Stepankova, J., Brabec, V. (2012), Antitumor carboplatin is more toxic in tumor cells when photoactivated: enhanced DNA binding, JOURNAL OF BIOLOGICAL INORGANIC CHEMISTRY 17, 891-898 [AIS=1.029, IF=3.289 VH]
• Florian, J., Kasparkova, J., Farrell, NP., Brabec, V. (2012), Thermodynamic stability and energetics of DNA duplexes containing major intrastrand cross-links of second-generation antitumor dinuclear Pt-II complexes, JOURNAL OF BIOLOGICAL INORGANIC CHEMISTRY 17, 187-196 [AIS=1.029, IF=3.289 VH]
• Kovacova, V., Janousek, B. (2012), Bisprimer-A Program for the Design of Primers for Bisulfite-Based Genomic Sequencing of Both Plant and Mammalian DNA Samples, JOURNAL OF HEREDITY 103, 308-312 [AIS=0.972, IF=2.799 V]
• Talianova, M., Zluvova, J., Hobza, R., Vyskot, B., Janousek, B. (2012), Identification and characterization of a bacteria-like sequence in the genome of some Silene species, BIOLOGIA PLANTARUM 56, 247-253 [AIS=0.276, IF=1.974 V]
• Olivova, R., Stepankova, J., Muchova, T., Novohradsky, V., Novakova, O., Vrana, O., Kasparkova, J., Brabec, V. (2012), Mechanistic insights into toxic effects of a benzotriazolate-bridged dinuclear platinum(II) compound in tumor cells, INORGANICA CHIMICA ACTA 393, 204-211 [AIS=0.393, IF=1.846 VH]
• Smetana, O., Siroky, J., Houlne, G., Opatrny, Z., Chaboute, ME. (2012), Non-apoptotic programmed cell death with paraptotic-like features in bleomycin-treated plant cells is suppressed by inhibition of ATM/ATR pathways or NtE2F overexpression, JOURNAL OF EXPERIMENTAL BOTANY 63, 2631-2644 [AIS=1.597, IF=5.364]

2011

• Malina, J., Kasparkova, J., Farrell, NP., Brabec, V. (2011), Walking of antitumor bifunctional trinuclear Pt-II complex on double-helical DNA, NUCLEIC ACIDS RESEARCH 39, 720-728 [AIS=3.001, IF=7.479 VH]
• Kisova, A., Zerzankova, L., Habtemariam, A., Sadler, PJ., Brabec, V., Kasparkova, J. (2011), Differences in the Cellular Response and Signaling Pathways between Cisplatin and Monodentate Organometallic Ru(II) Antitumor Complexes Containing a Terphenyl Ligand, MOLECULAR PHARMACEUTICS 8, 949-957 [AIS=1.56, IF=5.4 VH]
• Olivova, R., Kasparkova, J., Vrana, O., Vojtiskova, M., Suchankova, T., Novakova, O., He, WJ., Guo, ZJ., Brabec, V. (2011), Unique DNA Binding Mode of Antitumor Trinuclear Tridentate Platinum(II) Compound, MOLECULAR PHARMACEUTICS 8, 2368-2378 [AIS=1.56, IF=5.4 VH]
• Kostrhunova, H., Malina, J., Pickard, AJ., Stepankova, J., Vojtiskova, M., Kasparkova, J., Muchova, T., Rohlfing, ML., Bierbach, U., Brabec, V. (2011), Replacement of a Thiourea with an Amidine Group in a Monofunctional Platinum-Acridine Antitumor Agent. Effect on DNA Interactions, DNA Adduct Recognition and Repair, MOLECULAR PHARMACEUTICS 8, 1941-1954 [AIS=1, IF=5 VH]
• Stepankova, J., Studenovsky, M., Malina, J., Kasparkova, J., Liskova, B., Novakova, O., Ulbrich, K., Brabec, V. (2011), DNA interactions of 2-pyrrolinodoxorubicin, a distinctively more potent daunosamine-modified analogue of doxorubicin, BIOCHEMICAL PHARMACOLOGY 82, 227-235 [AIS=1.297, IF=4.889 VH]
• Malina, J., Farrell, NP., Brabec, V. (2011), DNA Interstrand Cross-Links of an Antitumor Trinuclear Platinum(II) Complex: Thermodynamic Analysis and Chemical Probing, CHEMISTRY-AN ASIAN JOURNAL 6, 1566-1574 [AIS=1.316, IF=4.188 VH]
• Liu, Z., Habtemariam, A., Pizarro, AM., Fletcher, SA., Kisova, A., Vrana, O., Salassa, L., Bruijnincx, PCA., Clarkson, GJ., Brabec, V., Sadler, PJ. (2011), Organometallic Half-Sandwich Iridium Anticancer Complexes, JOURNAL OF MEDICINAL CHEMISTRY 54, 3011-3026 [AIS=1.289, IF=4.802 H]
• van Rijt, SH., Kostrhunova, H., Brabec, V., Sadler, PJ. (2011), Functionalization of Osmium Arene Anticancer Complexes with (Poly)arginine: Effect on Cellular Uptake, Internalization, and Cytotoxicity, BIOCONJUGATE CHEMISTRY 22, 218-226 [AIS=1.363, IF=4.35 H]
• Triantafillidi, K., Karidi, K., Novakova, O., Malina, J., Garoufis, A. (2011), DNA binding selectivity of oligopyridine-ruthenium(II)-lysine conjugate, DALTON TRANSACTIONS 40, 472-483 [AIS=0.882, IF=4.081 H]
• Westendorf, AF., Zerzankova, L., Salassa, L., Sadler, PJ., Brabec, V., Bednarski, PJ. (2011), Influence of pyridine versus piperidine ligands on the chemical, DNA binding and cytotoxic properties of light activated trans,trans,trans-[Pt(N(3))(2)(OH)(2)(NH(3))(L)], JOURNAL OF INORGANIC BIOCHEMISTRY 105, 652-662 [AIS=0.871, IF=3.317 H]
• Zoldakova, M., Biersack, B., Kostrhunova, H., Ahmad, A., Padhye, S., Sarkar, FH., Schobert, R., Brabec, V. (2011), (Carboxydiamine)Pt(II) complexes of a combretastatin A-4 analogous chalcone: the influence of the diamine ligand on DNA binding and anticancer effects, MEDCHEMCOMM 2, 493-499 [AIS=0, IF=0 H]

2010

• Alkhader, S., Ezra, A., Kasparkova, J., Brabec, V., Yavin, E. (2010), A Metal-Free DNA Nuclease Based on a Cyclic Peptide Scaffold, BIOCONJUGATE CHEMISTRY 21, 1425-1431 [AIS=1.348, IF=4.35 H]
• Biton, A., Ezra, A., Kasparkova, J., Brabec, V., Yavin, E. (2010), DNA Photocleavage by DNA and DNA-LNA Amino Acid-Dye Conjugates, BIOCONJUGATE CHEMISTRY 21, 616-621 [AIS=1.348, IF=4.35 H]
• Kostrhunova, H., Kasparkova, J., Gibson, D., Brabec, V. (2010), Studies on Cellular Accumulation of Satraplatin and Its Major Metabolite JM118 and Their Interactions with Glutathione, MOLECULAR PHARMACEUTICS 7, 2093-2102 [AIS=1.428, IF=5.408 VH]
• Kostrhunova, H., Vrana, O., Suchankova, T., Gibson, D., Kasparkova, J., Brabec, V. (2010), Different Features of the DNA Binding Mode of Antitumor cis-Amminedichlorido(cyclohexylamine)platinum(H) (JM118) and Cisplatin in Vitro, CHEMICAL RESEARCH IN TOXICOLOGY 23, 1833-1842 [AIS=0.967, IF=3.74 VH]
• Novakova, O., Malina, J., Suchankova, T., Kasparkova, J., Bugarcic, T., Sadler, PJ., Brabec, V. (2010), Energetics, Conformation, and Recognition of DNA Duplexes Modified by Monodentate Ru-II Complexes Containing Terphenyl Arenes, CHEMISTRY-A EUROPEAN JOURNAL 16, 5744-5754 [AIS=1.593, IF=5.382 VH]
• Zerzankova, L., Suchankova, T., Vrana, O., Farrell, NP., Brabec, V., Kasparkova, J. (2010), Conformation and recognition of DNA modified by a new antitumor dinuclear Pt-II complex resistant to decomposition by sulfur nucleophiles, BIOCHEMICAL PHARMACOLOGY 79, 112-121 [AIS=1.166, IF=4.254 VH]
• Kasparkova, J., Suchankova, T., Halamikova, A., Zerzankova, L., Vrana, O., Margiotta, N., Natile, G., Brabec, V. (2010), Cytotoxicity, cellular uptake, glutathione and DNA interactions of an antitumor large-ring Pt-II chelate complex incorporating the cis-1,4-diaminocyclohexane carrier ligand, BIOCHEMICAL PHARMACOLOGY 79, 552-564 [AIS=1.166, IF=4.254 VH]
• Zerzankova, L., Kostrhunova, H., Vojtiskova, M., Novakova, O., Suchankova, T., Lin, MX., Guo, ZJ., Kasparkova, J., Brabec, V. (2010), Mechanistic insights into antitumor effects of new dinuclear cis Pt-II complexes containing aromatic linkers, BIOCHEMICAL PHARMACOLOGY 80, 344-351 [AIS=1.166, IF=4.254 VH]

2009

• Malina, J., Vrana, O., Brabec, V. (2009), Mechanistic studies of the modulation of cleavage activity of topoisomerase I by DNA adducts of mono- and bi-functional Pt-II complexes, NUCLEIC ACIDS RESEARCH 37, 5432-5442 [AIS=3, IF=7.48 VH]
• Novakova, O., Malina, J., Kasparkova, J., Halamikova, A., Bernard, V., Intini, F., Natile, G., Brabec, V. (2009), Energetics, Conformation, and Recognition of DNA Duplexes Modified by Methylated Analogues of [PtCl(dien)](+), CHEMISTRY-A EUROPEAN JOURNAL 15, 6211-6221 [AIS=1.593, IF=5.382 VH]
• Ruhayel, RA., Moniodis, JJ., Yang, XH., Kasparkova, J., Brabec, V., Berners-Price, SJ., Farrell, NP. (2009), Factors Affecting DNA-DNA Interstrand Cross-Links in the Antiparallel 3 '-3 ' Sense: A Comparison with the 5 '-5 ' Directional Isomer, CHEMISTRY-A EUROPEAN JOURNAL 15, 9365-9374 [AIS=1.593, IF=5.382 VH]
• Krause-Heuer, AM., Grunert, R., Kuhne, S., Buczkowska, M., Wheate, NJ., Le Pevelen, DD., Boag, LR., Fisher, DM., Kasparkova, J., Malina, J., Bednarski, PJ., Brabec, V., Aldrich-Wright, JR. (2009), Studies of the Mechanism of Action of Platinum(II) Complexes with Potent Cytotoxicity in Human Cancer Cells, JOURNAL OF MEDICINAL CHEMISTRY 52, 5474-5484 [AIS=1.285, IF=4.802 H]
• Triantafillidi, K., Karidi, K., Malina, J., Garoufis, A. (2009), Oligopyridine-ruthenium(II)-amino acid conjugates: synthesis, characterization, DNA binding properties and interactions with the oligonucleotide duplex d(5 '-CGCGCG-3 ')(2), DALTON TRANSACTIONS, 6403-6415 [AIS=0.881, IF=4.081 H]
• Heringova, P., Kasparkova, J., Brabec, V. (2009), DNA adducts of antitumor cisplatin preclude telomeric sequences from forming G quadruplexes, JOURNAL OF BIOLOGICAL INORGANIC CHEMISTRY 14, 959-968 [AIS=1.195, IF=3.415 VH]
• Suchankova, T., Vojtiskova, M., Reedijk, J., Brabec, V., Kasparkova, J. (2009), DNA and glutathione interactions in cell-free media of asymmetric platinum(II) complexes cis- and trans-[PtCl2(isopropylamine)(1-methylimidazole)]: relations to their different antitumor effects, JOURNAL OF BIOLOGICAL INORGANIC CHEMISTRY 14, 75-87 [AIS=1.195, IF=3.415 VH]
• Masek, V., Anzenbacherova, E., Machova, M., Brabec, V., Anzenbacher, P. (2009), Interaction of antitumor platinum complexes with human liver microsomal cytochromes P450, ANTI-CANCER DRUGS 20, 305-311 [AIS=0.576, IF=2.23 H]
• Novakova, O., Nazarov, AA., Hartinger, CG., Keppler, BK., Brabec, V. (2009), DNA interactions of dinuclear Ru-II arene antitumor complexes in cell-free media, BIOCHEMICAL PHARMACOLOGY 77, 364-374 [AIS=1.166, IF=4.254 VH]
• Triantafillidi K., Karidi K., Malina J., Garoufis A. (2009), Oligopyridine-ruthenium(II)-amino acid conjugates: synthesis, characterization, DNA binding properties and interactions with the oligonucleotide duplex d(5 '-CGCGCG-3 ')(2), DALTON TRANSACTIONS 32, 6403-6415 [AIS=0.882, IF=4.081 H]
• Methling K., Reszka P., Lalk M., Vrana O., Scheuch E., Siegmund W., Terhaag B., Bednarski PJ. (2009), Investigation of the in Vitro Metabolism of the Analgesic Flupirtine, DRUG METABOLISM AND DISPOSITION 37, 479-493 [AIS=0.921, IF=3.743 H]

2008

• Malina, J., Hannon, MJ., Brabec, V. (2008), DNA binding of dinuclear iron(II) metallosupramolecular cylinders. DNA unwinding and sequence preference, NUCLEIC ACIDS RESEARCH 36, 3630-3638 [AIS=3, IF=7.48 VH]
• Malina, J., Hannon, MJ., Brabec, V. (2008), Interaction of Dinuclear Ruthenium(II) Supramolecular Cylinders with DNA: Sequence-Specific Binding, Unwinding, and Photocleavage, CHEMISTRY-A EUROPEAN JOURNAL 14, 10408-10414 [AIS=1.593, IF=5.382 VH]
• Kasparkova, J., Vojtiskova, M., Natile, G., Brabec, V. (2008), Unique properties of DNA interstrand cross-links of antitumor oxaliplatin and the effect of chirality of the carrier ligand, CHEMISTRY-A EUROPEAN JOURNAL 14, 1330-1341 [AIS=1.593, IF=5.382 VH]
• Hegmans, A., Kasparkova, J., Vrana, O., Kelland, LR., Brabec, V., Farrell, NP. (2008), Amide-based Prodrugs of spermidine-bridged dinuclear platinum. Synthesis, DNA binding, and biological activity, JOURNAL OF MEDICINAL CHEMISTRY 51, 2254-2260 [AIS=1.285, IF=4.802 H]
• Bugarcic, T., Novakova, O., Halamikova, A., Zerzankova, L., Vrana, O., Kasparkova, J., Habtemariam, A., Parsons, S., Sadler, PJ., Brabec, V. (2008), Cytotoxicity, cellular uptake, and DNA interactions of new monodentate ruthenium(II) complexes containing terphenyl arenes, JOURNAL OF MEDICINAL CHEMISTRY 51, 5310-5319 [AIS=1.285, IF=4.802 VH]
• Kostrhunova, H., Florian, J., Novakova, O., Peacock, AFA., Sadler, PJ., Brabec, V. (2008), DNA interactions of monofunctional organometallic osmium(II) antitumor complexes in cell-free media, JOURNAL OF MEDICINAL CHEMISTRY 51, 3635-3643 [AIS=1.285, IF=4.802 VH]
• de Mier-Vinue, J., Gay, M., Montana, AM., Saez, RI., Moreno, V., Kasparkova, J., Vrana, O., Heringova, P., Brabec, V., Boccarelli, A., Coluccia, M., Natile, G. (2008), Synthesis, biophysical studies, and antiproliferative activity of platinum(II) complexes having 1,2-bis(aminomethyl)carbobicyclic ligands, JOURNAL OF MEDICINAL CHEMISTRY 51, 424-431 [AIS=1.285, IF=4.802 H]
• Bugarcic, T., Habtemariam, A., Stepankova, J., Heringova, P., Kasparkova, J., Deeth, RJ., Johnstone, RDL., Prescimone, A., Parkin, A., Parsons, S., Brabec, V., Sadler, PJ. (2008), The Contrasting Chemistry and Cancer Cell Cytotoxicity of Bipyridine and Bipyridinediol Ruthenium(II) Arene Complexes, INORGANIC CHEMISTRY 47, 11470-11486 [AIS=1.018, IF=4.657 H]
• Kasparkova, J., Marini, V., Bursova, V., Brabec, V. (2008), Biophysical Studies on the Stability of DNA Intrastrand Cross-Links of Transplatin, BIOPHYSICAL JOURNAL 95, 4361-4371 [AIS=1.917, IF=4.39 VH]
• Castellano-Castillo, M., Kostrhunova, H., Marini, V., Kasparkova, J., Sadler, PJ., Malinge, JM., Brabec, V. (2008), Binding of mismatch repair protein MutS to mispaired DNA adducts of intercalating ruthenium(II) arene complexes, JOURNAL OF BIOLOGICAL INORGANIC CHEMISTRY 13, 993-999 [AIS=1.195, IF=3.415 VH]

2007

• Mackay, FS., Woods, JA., Heringova, P., Kasparkova, J., Pizarro, AM., Moggach, SA., Parsons, S., Brabec, V., Sadler, PJ. (2007), A potent cytotoxic photoactivated platinum complex, PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA 104, 20743-20748 [AIS=4.86, IF=9.43 H]
• Gallmeier, E., Hucl, T., Brody, JR., Dezentje, DA., Tahir, K., Kasparkova, J., Brabec, V., Bachman, KE., Kern, SE. (2007), High-throughput screening identifies novel agents eliciting hypersensitivity in Fanconi pathway-deficient cancer cells, CANCER RESEARCH 67, 2169-2177 [AIS=2.92, IF=7.543 H]
• Chvalova, K., Brabec, V., Kasparkova, J. (2007), Mechanism of the formation of DNA-protein cross-links by antitumor cisplatin, NUCLEIC ACIDS RESEARCH 35, 1812-1821 [AIS=3, IF=7.48 VH]
• Malina, J., Hannon, MJ., Brabec, V. (2007), Recognition of DNA three-way junctions by metallosupramolecular cylinders: Gel electrophoresis studies, CHEMISTRY-A EUROPEAN JOURNAL 13, 3871-3877 [AIS=1.593, IF=5.382 VH]
• Knipp, M., Karotki, AV., Chesnov, S., Natile, G., Sadler, PJ., Brabec, V., Vasak, M. (2007), Reaction of Zn(7)Metallothionein with cis- and trans-[Pt(N-donor)(2)Cl-2] anticancer complexes: trans-Pt-II complexes retain their N-donor ligands, JOURNAL OF MEDICINAL CHEMISTRY 50, 4075-4086 [AIS=1.285, IF=4.802 H]
• Melchart, M., Habtemariam, A., Novakova, O., Moggach, SA., Fabbiani, FPA., Parsons, S., Brabec, V., Sadler, PJ. (2007), Bifunctional amine-tethered Ruthenium(II) arene complexes form monofunctional adducts on DNA, INORGANIC CHEMISTRY 46, 8950-8962 [AIS=1.018, IF=4.657 H]
• Magennis, SW., Habtemariam, A., Novakova, O., Henry, JB., Meier, S., Parsons, S., Oswald, IDH., Brabec, V., Sadler, PJ. (2007), Dual triggering of DNA binding and fluorescence via photoactivation of a dinuclear ruthenium(II) arene complex, INORGANIC CHEMISTRY 46, 5059-5068 [AIS=1.018, IF=4.657 H]
• Malina, J., Novakova, O., Vojtiskova, M., Natile, G., Brabec, V. (2007), Conformation of DNA GG intrastrand cross-link of antitumor oxaliplatin and its enantiomeric analog, BIOPHYSICAL JOURNAL 93, 3950-3962 [AIS=1.917, IF=4.39 VH]
• Brabec, V., Christofis, P., Slamova, M., Kostrhunova, H., Novakova, O., Najajreh, Y., Gibson, D., Kagparkova, J. (2007), DNA interactions of new cytotoxic tetrafunctional dinuidear platinum complex trans,trans-[{PtCl2(NH3)}(2)(piperazine)], BIOCHEMICAL PHARMACOLOGY 73, 1887-1900 [AIS=1.166, IF=4.254 VH]
• Halamikova, A., Vrana, D., Kasparkova, J., Brabec, V. (2007), Biochemical studies of the thermal effects on DNA modifications by the antitumor cisplatin and their repair, CHEMBIOCHEM 8, 2008-2015 [AIS=1.362, IF=3.824 VH]
• Myari, A., Hadjiliadis, N., Garoufis, A., Malina, J., Brabec, V. (2007), NMR analysis of duplex d(CGCGATCGCG)(2) modified by Lambda- and Delta-[Ru(bpy)(2)(m-GHK)]Cl-2 and DNA photocleavage study, JOURNAL OF BIOLOGICAL INORGANIC CHEMISTRY 12, 279-292 [AIS=1.195, IF=3.415 H]
• Peberdy, JC., Malina, J., Khalid, S., Hannon, MJ., Rodger, A. (2007), Influence of surface shape on DNA binding of bimetallo helicates, JOURNAL OF INORGANIC BIOCHEMISTRY 101, 1937-1945 [AIS=0.909, IF=3.252 H]
• Moriarity, B., Novakova, O., Farrell, N., Brabec, V., Kasparkova, J. (2007), 1,2-GG intrastrand cross-link of antitumor dinuclear bifunctional platinum compound with spermidine linker inhibits DNA polymerization more effectively than the cross-link of conventional cisplatin, ARCHIVES OF BIOCHEMISTRY AND BIOPHYSICS 459, 264-272 [AIS=0.975, IF=3.046 VH]
• Vrana, O., Masek, V., Drazan, V., Brabec, V. (2007), Raman spectroscopy of DNA modified by intrastrand cross-links of antitumor cisplatin, JOURNAL OF STRUCTURAL BIOLOGY 159, 1-8 [AIS=1.91, IF=3.673 VH]

2006

• Najajreh, Y., Khazanov, E., Jawbry, S., Ardeli-Tzaraf, Y., Perez, JM., Kasparkova, J., Brabec, V., Barenholz, Y., Gibson, D. (2006), Cationic nonsymmetric transplatinum complexes with piperidinopiperidine ligands. Preparation, characterization, in vitro cytotoxicity, in vivo toxicity, and anticancer efficacy studies, JOURNAL OF MEDICINAL CHEMISTRY 49, 4665-4673 [AIS=1.285, IF=4.802 H]
• Najajreh, Y., Ardeli-Tzaraf, Y., Kasparkova, J., Heringova, P., Prilutski, D., Balter, L., Jawbry, S., Khazanov, E., Perez, JM., Barenholz, Y., Brabec, V., Gibson, D. (2006), Interactions of platinum complexes containing cationic, bicyclic, nonplanar piperidinopiperidine ligands with biological nucleophiles, JOURNAL OF MEDICINAL CHEMISTRY 49, 4674-4683 [AIS=1.285, IF=4.802 H]
• Ramos-Lima, FJ., Vrana, O., Quiroga, AG., Navarro-Ranninger, CN., Halamikova, A., Rybnickova, H., Hejmalova, L., Brabec, V. (2006), Structural characterization, DNA interactions, and cytotoxicity of new transplatin analogues containing one aliphatic and one planar heterocyclic amine ligand, JOURNAL OF MEDICINAL CHEMISTRY 49, 2640-2651 [AIS=1.285, IF=4.802 VH]
• Heringova, P., Woods, J., Mackay, FS., Kasparkova, J., Sadler, PJ., Brabec, V. (2006), Transplatin is cytotoxic when photoactivated: Enhanced formation of DNA cross-links, JOURNAL OF MEDICINAL CHEMISTRY 49, 7792-7798 [AIS=1.285, IF=4.802 VH]
• Kasparkova, J., Novakova, O., Vrana, O., Intini, F., Natile, G., Brabec, V. (2006), Molecular aspects of antitumor effects of a new platinum(IV) drug, MOLECULAR PHARMACOLOGY 70, 1708-1719 [AIS=1.55, IF=4.53 VH]
• Bodo, J., Hunakova, L., Kvasnicka, P., Jakubikova, J., Duraj, J., Kasparkova, J., Sedlak, J. (2006), Sensitisation for cisplatin-induced apoptosis by isothiocyanate E-4IB leads to signalling pathways alterations, BRITISH JOURNAL OF CANCER 95, 1348-1353 [AIS=1.467, IF=4.346 H]
• Valik, M., Malina, J., Palivec, L., Foltynova, J., Tkadlecova, M., Urbanova, M., Brabec, V., Kral, V. (2006), Troger's base scaffold in racemic and chiral fashion as a spacer for bisdistamycin formation. Synthesis and DNA binding study, TETRAHEDRON 62, 8591-8600 [AIS=0.79, IF=3.22 H]
• Brabec, V., Stehlikova, KN., Malina, J., Vojtiskova, M., Kasparkova, J. (2006), Thermodynamic properties of damaged DNA and its recognition by xeroderma pigmentosum group A protein and replication protein A, ARCHIVES OF BIOCHEMISTRY AND BIOPHYSICS 446, 1-10 [AIS=0.975, IF=3.046 VH]
• Chvalova, K., Kasparkova, J., Farrell, N., Brabec, V. (2006), Deoxyribonuclease I footprinting reveals different DNA binding modes of bifunctional platinum complexes, FEBS JOURNAL 273, 3467-3478 [AIS=1.219, IF=3.042 VH]
• Stehlikova, K., Kasparkova, J., Novakova, O., Martinez, A., Moreno, V., Brabec, V. (2006), Recognition of DNA modified by trans-[PtCl2NH3(4-hydroxymethylpyridine)] by tumor suppressor protein p53 and character of DNA adducts of this cytotoxic complex, FEBS JOURNAL 273, 301-314 [AIS=1.219, IF=3.042 VH]
• Brabec, V., Novakova, O. (2006), DNA binding mode of ruthenium complexes and relationship to tumor cell toxicity, DRUG RESISTANCE UPDATES 9, 111-122 [AIS=2.48, IF=12.581 VH]
• Pivonkova, H., Brazdova, M., Kasparkova, J., Brabec, V., Fojta, M. (2006), Recognition of cisplatin-damaged DNA by p53 protein: Critical role of the p53 C-terminal domain, BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS 339, 477-484 [AIS=0.905, IF=2.548 V]

2005

• Najajreh, Y., Prilutski, D., Ardeli-Tzaraf, Y., Perez, JM., Khazanov, E., Barenholz, Y., Kasparkova, J., Brabec, V., Gibson, D. (2005), Structure and unique interactions with DNA of a cationic trans-platinum complex with the nonplanar bicyclic piperidinopiperidine ligand, ANGEWANDTE CHEMIE-INTERNATIONAL EDITION 44, 2885-2887 [AIS=3.296, IF=11.829 H]
• Marini, V., Christofis, P., Novakova, O., Kasparkova, J., Farrell, N., Brabec, V. (2005), Conformation, protein recognition and repair of DNA interstrand and intrastrand cross-links of antitumor trans-[PtCl2(NH3)(thiazole)], NUCLEIC ACIDS RESEARCH 33, 5819-5828 [AIS=3, IF=7.48 VH]
• Novakova, O., Kasparkova, J., Bursova, V., Hofr, C., Vojtiskova, M., Chen, HM., Sadler, PJ., Brabec, V. (2005), Conformation of DNA modified by monofunctional Ru(II) arene complexes: Recognition by DNA binding proteins and repair. Relationship to cytotoxicity, CHEMISTRY & BIOLOGY 12, 121-129 [AIS=2.536, IF=6.523 H]
• Delalande, O., Malina, J., Brabec, V., Kozelka, J. (2005), Chiral differentiation of DNA adducts formed by enantiomeric analogues of antitumor cisplatin is sequence-dependent, BIOPHYSICAL JOURNAL 88, 4159-4169 [AIS=1.917, IF=4.39 VH]
• Bursova, V., Kasparkova, J., Hofr, C., Brabec, V. (2005), Effects of monofunctional adducts of Platinum(II) complexes on thermodynamic stability and energetics of DNA duplexes, BIOPHYSICAL JOURNAL 88, 1207-1214 [AIS=1.917, IF=4.39 VH]
• Najajreh, Y., Kasparkova, J., Marini, V., Gibson, D., Brabec, V. (2005), Structural characterization and DNA interactions of new cytotoxic transplatin analogues containing one planar and one nonplanar heterocyclic amine ligand, JOURNAL OF BIOLOGICAL INORGANIC CHEMISTRY 10, 722-731 [AIS=1.195, IF=3.415 VH]
• Mitchell, EP., Sabin, C., Snajdrova, L., Pokorna, M., Perret, S., Gautier, C., Hofr, C., Gilboa-Garber, N., Koca, J., Wimmerova, M., Imberty, A. (2005), High affinity fucose binding of Pseudomonas aeruginosa lectin PA-IIL: 1.0 angstrom resolution crystal structure of the complex combined with thermodynamics and computational chemistry approaches, PROTEINS-STRUCTURE FUNCTION AND BIOINFORMATICS 58, 735-746 [AIS=1.285, IF=3.085 H]
• Hofr, C., Brabec, V. (2005), Thermal stability and energetics of 15-mer DNA duplex interstrand crosslinked by trans-diamminedichloroplatinum(II), BIOPOLYMERS 77, 222-229 [AIS=0.871, IF=2.605 VH]
• Malina, J., Voitiskova, M., Brabec, V., Diakos, CI., Hambley, TW. (2005), DNA adducts of the enantiomers of the Pt(II) complexes of the ahaz ligand (ahaz=3-aminohexahydroazepine) and recognition of these adducts by HMG domain proteins, BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS 332, 1034-1041 [AIS=0.905, IF=2.548 H]
• Brabec, V., Kasparkova, J. (2005), Modifications of DNA by platinum complexes - Relation to resistance of tumors to platinum antitumor drugs, DRUG RESISTANCE UPDATES 8, 131-146 [AIS=2.48, IF=12.581 VH]

2004

• Prokop, R., Kasparkova, J., Novakova, O., Marini, V., Pizarro, AM., Navarro-Ranninger, C., Brabec, V. (2004), DNA interactions of new antitumor platinum complexes with trans geometry activated by a 2-metylbutylamine or sec-butylamine ligand, BIOCHEMICAL PHARMACOLOGY 67, 1097-1109 [AIS=1.166, IF=4.254 VH]
• Kloster, M., Kostrhunova, H., Zaludova, R., Malina, J., Kasparkova, J., Brabec, V., Farrell, N. (2004), Trifunctional dinuclear platinum complexes as DNA-protein cross-linking agent, BIOCHEMISTRY 43, 7776-7786 [AIS=1.315, IF=3.226 H]
• Kasparkova, J., Fojta, M., Farrell, N., Brabec, V. (2004), Differential recognition by the tumor suppressor protein p53 of DNA modified by the novel antitumor trinuclear platinum drug BBR3464 and cisplatin, NUCLEIC ACIDS RESEARCH 32, 5546-5552 [AIS=3, IF=7.48 VH]

2003

• Chen, HM., Parkinson, JA., Novakova, O., Bella, J., Wang, FY., Dawson, A., Gould, R., Parsons, S., Brabec, V., Sadler, PJ. (2003), Induced-fit recognition of DNA by organometallic complexes with dynamic stereogenic centers, PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA 100, 14623-14628 [AIS=4.86, IF=9.43 VH]
• Kasparkova, J., Novakova, O., Najajreh, Y., Gibson, D., Perez, JM., Brabec, V. (2003), Effects of a piperidine ligand on DNA modification by antitumor cisplatin analogues, CHEMICAL RESEARCH IN TOXICOLOGY 16, 1424-1432 [AIS=0.963, IF=3.74 VH]
• Kasparkova, J., Mackay, FS., Brabec, V., Sadler, PJ. (2003), Formation of platinated GG cross-links on DNA by photoactivation of a platinum(IV) azide complex, JOURNAL OF BIOLOGICAL INORGANIC CHEMISTRY 8, 741-745 [AIS=1.195, IF=3.415 H]
• Kasparkova, J., Novakova, O., Farrell, N., Brabec, V. (2003), DNA binding by antitumor trans[PtCl2(NH3)(thiazole)]. Protein recognition and nucleotide excision repair of monofunctional adductst, BIOCHEMISTRY 42, 792-800 [AIS=1.315, IF=3.226 H]
• Novakova, O., Chen, HM., Vrana, O., Rodger, A., Sadler, PJ., Brabec, V. (2003), DNA interactions of monofunctional organometallic ruthenium(II) antitumor complexes in cell-free media, BIOCHEMISTRY 42, 11544-11554 [AIS=1.315, IF=3.226 H]
• Fridman, AS., Brabec, V., Haroutiunian, SG., Wartell, RM., Lando, DY. (2003), Melting of cross-linked DNA v. cross-linking effect caused by local stabilization of the double helix, JOURNAL OF BIOMOLECULAR STRUCTURE & DYNAMICS 20, 533-545 [AIS=0.32, IF=1.124 H]
• Novakova, O., Kasparkova, J., Malina, J., Natile, G., Brabec, V. (2003), DNA-protein cross-linking by trans-[PtCl2(E-iminoether)(2)]. A concept for activation of the trans geometry in platinum antitumor complexes, NUCLEIC ACIDS RESEARCH 31, 6450-6460 [AIS=3, IF=7.48 VH]
• Kasparkova, J., Novakova, O., Marini, V., Najajreh, Y., Gibson, D., Perez, JM., Brabec, V. (2003), Activation of trans geometry in bifunctional mononuclear platinum complexes by a piperidine ligand - Mechanistic studies on antitumor action, JOURNAL OF BIOLOGICAL CHEMISTRY 278, 47516-47525 [AIS=2.223, IF=5.328 VH]
• Fojta, M., Pivonkova, H., Brazdova, M., Kovarova, L., Palecek, E., Pospisilova, S., Vojtesek, B., Kasparkova, J., Brabec, V. (2003), Recognition of DNA modified by antitumor cisplatin by "latent" and "active" protein p53, BIOCHEMICAL PHARMACOLOGY 65, 1305-1316 [AIS=1.166, IF=4.254 V]
• Kasparkova, J., Marini, V., Najajreh, Y., Gibson, D., Brabec, V. (2003), DNA binding mode of the cis and trans geometries of new antitumor nonclassical platinum complexes containing piperidine, piperazine, or 4-picoline ligand in cell-free media. Relations to their activity in cancer cell lines, BIOCHEMISTRY 42, 6321-6332 [AIS=1.315, IF=3.226 VH]
• Kasparkova, J., Delalande, O., Stros, M., Elizondo-Riojas, MA., Vojtiskova, M., Kozelka, J., Brabec, V. (2003), Recognition of DNA interstrand cross-link of antitumor cisplatin by HMGB1 protein, BIOCHEMISTRY 42, 1234-1244 [AIS=1.315, IF=3.226 VH]

2002

• Stehlikova, K., Kostrhunova, H., Kasparkova, J., Brabec, V. (2002), DNA bending and unwinding due to the major 1,2-GG intrastrand cross-link formed by antitumor cis-diamminedichloroplatinum(II) are flanking-base independent, NUCLEIC ACIDS RESEARCH 30, 2894-2898 [AIS=3, IF=7.48 VH]
• Malina, J., Kasparkova, J., Natile, G., Brabec, V. (2002), Recognition of major DNA adducts of enantiomeric cisplatin analogs by HMG box proteins and nucleotide excision repair of these adducts, CHEMISTRY & BIOLOGY 9, 629-638 [AIS=2.536, IF=6.523 VH]
• Kasparkova, J., Zehnulova, J., Farrell, N., Brabec, V. (2002), DNA interstrand cross-links of the novel antitumor trinuclear platinum complex BBR3464 - Conformation, recognition by high mobility group domain proteins, and nucleotide excision, JOURNAL OF BIOLOGICAL CHEMISTRY 277, 48076-48086 [AIS=2.223, IF=5.328 H]
• McGregor, TD., Hegmans, A., Kasparkova, J., Neplechova, K., Novakova, O., Penazova, H., Vrana, O., Brabec, V., Farrell, N. (2002), A comparison of DNA binding profiles of dinuclear platinum compounds with polyamine linkers and the trinuclear platinum phase II clinical agent BBR3464, JOURNAL OF BIOLOGICAL INORGANIC CHEMISTRY 7, 397-404 [AIS=1.195, IF=3.415 H]
• Janovska, E., Novakova, O., Natile, G., Brabec, V. (2002), Differential genotoxic effects of antitumor trans-[PtCl2(E-iminoether)(2)] and cisplatin in Escherichia coli, JOURNAL OF INORGANIC BIOCHEMISTRY 90, 155-158 [AIS=0.909, IF=3.252 VH]
• Vrana, O., Brabec, V. (2002), L-Methionine inhibits reaction of DNA with anticancer cis-diamminedichloroplatinum(II), BIOCHEMISTRY 41, 10994-10999 [AIS=1.315, IF=3.226 VH]
• Dadak, V., Janiczek, O., Vrana, O. (2002), Cytochrome c forms complexes and is partly reduced at interaction with GPI-anchored alkaline phosphatase, BIOCHIMICA ET BIOPHYSICA ACTA-GENERAL SUBJECTS 1570, 9-18 [AIS=0.882, IF=2.958 H]
• Brabec, V., Kasparkova, J. (2002), Molecular aspects of resistance to antitumor platinum drugs, DRUG RESISTANCE UPDATES 5, 147-161 [AIS=2.48, IF=12.581 VH]
• Marini, V., Kasparkova, J., Novakova, O., Scolaro, LM., Romeo, R., Brabec, V. (2002), Biophysical analysis of natural, double-helical DNA modified by a dinuclear platinum(II) organometallic compound in a cell-free medium, JOURNAL OF BIOLOGICAL INORGANIC CHEMISTRY 7, 725-734 [AIS=1.195, IF=3.415 VH]
• Brabec, V. (2002), DNA modifications by antitumor platinum and ruthenium compounds: Their recognition and repair, PROGRESS IN NUCLEIC ACID RESEARCH AND MOLECULAR BIOLOGY, VOL 71 71, 1-68 [AIS=2.69, IF=2.29 VH]

2001

• Missura, M., Buterin, T., Hindges, R., Hubscher, U., Kasparkova, J., Brabec, V., Naegeli, H. (2001), Double-check probing of DNA bending and unwinding by XPA-RPA: an architectural function in DNA repair, EMBO JOURNAL 20, 3554-3564 [AIS=5.56, IF=8.993 H]
• Hofr, C., Farrell, N., Brabec, V. (2001), Thermodynamic properties of duplex DNA containing a site-specific d(GpG) intrastrand crosslink formed by an antitumor dinuclear platinum complex, NUCLEIC ACIDS RESEARCH 29, 2034-2040 [AIS=3, IF=7.48 VH]
• Zehnulova, J., Kasparkova, J., Farrell, N., Brabec, V. (2001), Conformation, recognition by high mobility group domain proteins, and nucleotide excision repair of DNA intrastrand cross-links of novel antitumor trinuclear platinum complex BBR3464, JOURNAL OF BIOLOGICAL CHEMISTRY 276, 22191-22199 [AIS=2.223, IF=5.328 H]
• Kasparkova, J., Pospisilova, S., Brabec, V. (2001), Different recognition of DNA modified by antitumor cisplatin and its clinically ineffective trans isomer by tumor suppressor protein p53, JOURNAL OF BIOLOGICAL CHEMISTRY 276, 16064-16069 [AIS=2.223, IF=5.328 VH]
• Hofr, C., Brabec, V. (2001), Thermal and thermodynamic properties of duplex DNA containing site-specific interstrand cross-link of antitumor cisplatin or its clinically ineffective trans isomer, JOURNAL OF BIOLOGICAL CHEMISTRY 276, 9655-9661 [AIS=2.223, IF=5.328 VH]
• Malina, J., Novakova, O., Keppler, BK., Alessio, E., Brabec, V. (2001), Biophysical analysis of natural, double-helical DNA modified by anticancer heterocyclic complexes of ruthenium(lll) in cell-free media, JOURNAL OF BIOLOGICAL INORGANIC CHEMISTRY 6, 435-445 [AIS=1.195, IF=3.415 VH]
• Kejnovsky, E., Vrana, J., Matsunaga, S., Soucek, P., Siroky, J., Dolezel, J., Vyskot, B. (2001), Localization of male-specifically expressed MROS genes of Silene latifolia by PCR on flow-sorted sex chromosomes and autosomes, GENETICS 158, 1269-1277 [AIS=1.962, IF=3.889 V]

2000

• Malina, J., Hofr, C., Maresca, L., Natile, G., Brabec, V. (2000), DNA interactions of antitumor cisplatin analogs containing enantiomeric amine ligands, BIOPHYSICAL JOURNAL 78, 2008-2021 [AIS=1.917, IF=4.39 VH]
• Novakova, O., Hofr, C., Brabec, V. (2000), Modification of natural, double-helical DNA by antitumor cis- and trans-[Cl-2(Me2SO4)(4)Ru] in cell-free media, BIOCHEMICAL PHARMACOLOGY 60, 1761-1771 [AIS=1.166, IF=4.254 VH]
• Kostrhunova, H., Brabec, V. (2000), Conformational analysis of site-specific DNA cross-links of cisplatin-distamycin conjugates, BIOCHEMISTRY 39, 12639-12649 [AIS=1.315, IF=3.226 VH]
• Kasparkova, J., Farrell, N., Brabec, V. (2000), Sequence specificity, conformation, and recognition by HMG1 protein of major DNA interstrand cross-links of antitumor dinuclear platinum complexes, JOURNAL OF BIOLOGICAL CHEMISTRY 275, 15789-15798 [AIS=2.223, IF=5.328 VH]
• Brabec, V., Neplechova, K., Kasparkova, J., Farrell, N. (2000), Steric control of DNA interstrand cross-link sites of trans platinum complexes: specificity can be dictated by planar nonleaving groups, JOURNAL OF BIOLOGICAL INORGANIC CHEMISTRY 5, 364-368 [AIS=1.195, IF=3.415 VH]