Sensitive electrochemical assays of DNA structure Electrochemical analysis of DNA

Published: CHIMICA OGGI-CHEMISTRY TODAY 27, 50-54 Authors: Bowater, RP., Davies, RJH., Palecek, E., Fojta, M. Year: 2009


Electrochemical methods have been used to study the structure and function of nucleic acids for more than 50 years. These approaches complement other experimental techniques, which we illustrate by using examples from studies of processes involved in the repair of DNA damage. The excellent sensitivity of the electrochemical approaches makes them good candidates for use as biosensors of a wide range of molecules and biological processes.