Free Radical Pathophysiology

Running projects

Novel nature-inspired organic semiconductors for bioelectronics

Project ID code: 17-24707S
Provider: GAČR
Years: 2017 - 2019
Solver: Jan Víteček

Stabilization of hypoxia-inducible factors in regulation of phenotypic and functional plasticity of neutrophil subpopulations in mouse

Project ID code: 17-26910Y
Provider: GAČR
Years: 2017 - 2019
Solver: Tomáš Perečko

Natural pseurotin alkaloids as significant immunotoxic contaminants

Project ID code: 17-18858S
Provider: GAČR
Years: 2017 - 2019
Solver: Lukáš Kubala

A complex role of nitro-fatty acids in regulation of cellular functions and processes: beyond the anti-inflammatory effect

Project ID code: 17-08066Y
Provider: GAČR
Years: 2017 - 2019
Solver: Michaela Pekarová

Importance of Toll-like receptors in intestinal epithelium response to cyanobacterial water bloom

Project ID code: 16-24949S
Provider: GAČR
Years: 2016 - 2018
Solver: Lenka Švihálková Šindlerová

Finished projects

Molecular mechanisms of serotoninergic system interactions with cells of immune system

Project ID code: LD14030
Provider: MŠMT
Years: 2014 - 2016
Solver: Číž, M.

Materials for integration of animal cells with organic electronics: towards future bioelectronic devices

Project ID code: 13-29358S
Provider: GAČR
Years: 2013 - 2016
Solver: Víteček, J. (spoluřešitel)

New Role for Nitrated Fatty Acid in Modulation of Phagocyte-derived Inflammatory Responses

Project ID code: 13-40824P
Provider: GA ČR
Years: 2013 - 2015
Solver: Ambrožová, G.

Role of L-arginine, methylarginines and their metabolism in regulation of endothelial homeostasis

Project ID code: 13-40882P
Provider: GAČR
Years: 2013 - 2014
Solver: Pekarová, M.

Importance of the interaction of myeloperoxidase with the endothelial glycocalyx for leukocyte recruitment and vascular fuction

Project ID code: P305/12/J038
Provider: GA ČR
Years: 2012 - 2014
Solver: Kubala, L.

The influence of L-arginine and its analogues on the generation of reactive oxygen and nitrogen species by professional phagocytes

Project ID code: 524/08/1753
Provider: GA ČR
Years: 2008 - 2012
Solver: Lojek, A

Role extracelulárního L-argininu v regulaci produkce oxidu dusnatého u endoteliálních buněk

Provider: Jihomoravské centrum pro mezinárodní mobilitu
Years: 2011 - 2011
Solver: Pekarová, M.

Interactions among collagen, platelets and phagocytes in modulation of reactive oxygen and nitrogen species production

Project ID code: OC10044
Provider: MŠMT
Years: 2010 - 2011
Solver: Číž, M.

Effect of polyunsaturated fatty acids and their metabolites on the physiological functions of professional phagocytes

Project ID code: OC08058
Provider: MŠMT
Years: 2008 - 2010
Solver: Lojek, A.

Role of hyaluronan of different molecular weight in the course of inflammation

Project ID code: 305/08/1704
Provider: GA ČR
Years: 2008 - 2010
Solver: Kubala, L.

Úloha krevních destiček, neutrofilů a složek mezibuněčné hmoty v zánětu. Analýza léčiv a perspektivních přírodních látek.

Project ID code: MEB0808106
Provider: MŠMT
Years: 2008 - 2009

Collagen, platelet and neutrophil interactions with respect to wound healing

Project ID code: 524/07/1511
Provider: GA ČR
Years: 2007 - 2009
Solver: Číž, M.

The role of uric acid in endothelial dysfunction

Project ID code: 204/07/P539
Provider: GA ČR
Years: 2007 - 2009
Solver: Papežíková, I.

The use of terestric bioluminescent bacteria in ecotoxicology

Project ID code: 525/06/1196
Provider: GA ČR
Years: 2006 - 2008
Solver: Lojek, A.

The role of free radicals in regulation of lung inflammation induced by acute or chronic exposition to endotoxin

Project ID code: 524/06/1197
Provider: GA ČR
Years: 2006 - 2008
Solver: Kubala, L.

Effects of carvedilol on metabolic activity of neutrophils and monocytes

Project ID code: 305/04/0896
Provider: GA ČR
Years: 2004 - 2006
Solver: Lojek, A.

The role of serotonin in mutual interactions of platelets and professional phagocytes

Project ID code: 524/04/0897
Provider: GA ČR
Years: 2004 - 2006
Solver: Číž, M.

The influence of hyaluronic acid on the functions and interactions of leukocytes and epithelial cells under physiological and inflammatory conditions

Project ID code: 524/02/0395
Provider: GA ČR
Years: 2002 - 2004
Solver: Lojek, A.

Antioxidative properties of flavonoids with respect to the oxidative burst of phagocyte and cooperation between phagocytes and endothelial cells

Project ID code: B6004204
Provider: GA AS ČR
Years: 2002 - 2004
Solver: Číž, M.

Understanding and modulation of the antioxidative defence mechanisms in oxidative stress

Project ID code: 524/01/1219
Provider: GA ČR
Years: 2001 - 2003
Solver: Číž, M.

Reactive oxygen and nitrogen metabolites generated by neutrophils under physiological and pathophysiological conditions

Project ID code: 524/00/1223
Provider: GA ČR
Years: 2000 - 2002
Solver: Lojek, A.

Influence of different time of ischemia adn reperfusion upon development of reperfusion injury intestine

Project ID code: 524/99/D022
Provider: GA ČR
Years: 1999 - 2002
Solver: Čížová, H.

The role of endogenous antioxidants in the regulation of post-ischemic oxidative stress

Project ID code: 524/98/0190
Provider: GA ČR
Years: 1998 - 2000
Solver: Číž, M.

Reactive oxygen species in relation to hemodialysis and kidney transplantation

Project ID code: 4796-3
Provider: IGA MZ ČR
Years: 1998 - 2000
Solver: Číž, M., Lojek, A.

The role of oxygen metabolites and nitric oxide in the development of intestinal reperfusion injury

Project ID code: 308/97/1141
Provider: GA ČR
Years: 1997 - 1999
Solver: Lojek, A.

Mechanisms of transplanted tissue injuries during their ischemia and reperfusion and prevention prospects

Project ID code: 2849-3
Provider: IGA MZ ČR
Years: 1995 - 1997
Solver: Číž, M., Lojek, A.

The role of oxygen free radicals in the hypoxic and reperfused tissues

Project ID code: 308/94/0387
Provider: GA ČR
Years: 1994 - 1996
Solver: Lojek, A.