Projekty
Běžící
Title / Agency | investigator/ year | ||
Lipid nutrition compounds-modulation of their effects and possibilities of practical application (IGA AVČR 1QS500040507) | A. Kozubík 2005 - 2009 | ||
Role of transforming growth factor-beta in regulation of proliferation, differentiation and apoptosis in prostate and colon cancer. (GA ČR 204/07/0834) | K. Souček 2007 - 2009 | ||
2007 - 2010 | GA ČR 310/07/0961 | The role of environmental pollutants in mechanisms regulating development of prostate carcinoma | M. Machala J. Topinka K. Souček |
2007 - 2011 | GA ČR 301/07/1557
| Novel anticancer platinum complexes ? mechanisms of their action and innovative chemotherapy | A. Kozubík |
2007 - 2011 | GA ČR 524/07/1178 | Importance of cell lipid changes during differentiation and apoptosis of colon epithelial cells | J. Hofmanová |
2009 - 2011 | GAČR 524/09/1337 | Interactions of Wnt and Ah receptor signaling in regulation of functions of liver cells | J. Vondráček |
2009 - 2011 | GAČR 305/09/1526 | The role of extracellular matrix-mediated cell adhesion in maintenance of colonic tissue homeostasis and in colon carcinogenesis | M. Hýžďalová |
2009 - 2011 | GAČR 204/09/J030 | Význam beta-arrestinu pro regulaci specificity ve Wnt signalizaci | V. Bryja |
2009 - 2012 |
GAČR 204/09/H058 |
Intercellular signalling in development and disease | V. Bryja J. Vondráček M. Jindra Z. Kozmik M. A. Jindrová |
2009 - 2012 | GAČR | Molekulární mechanismy vybraných patologických procesů v buňce | P. Anzenbacher J. Hofmanová |
2008 - 2011 | MZD 9600-4 | Modulation of signaling pathways leading to neuroendocrine differentiation in prostate cancer | K. Souček |
2008 - 2011 | MZD 9956-4
| Significance of asporin and other extracellular matrix proteins in invasive carcinomas of breast and prostate | J. Bouchal K. Souček |
2005 - 2008 | LACHEMA | Project LA-12 | A. Kozubík |
2008 - 2009 | MU Rektors Programme for Students? Creative Activity Support | Differences of adhesive properties and anoikis regulation in colon cells during interaction of fatty acids with cytokines of TNF family | L. Kočí |
2008 - 2009 | MU Rektor?s Programme for Students? Creative Activity Support | Role of TGFbeta family proteins in the cytokinetics of prostate and colon cancer cells | E. Lincová |
2008 - 2009 | MU Rektor?s Programme for Students? Creative Activity Support | Modulation possibilities of cytokine IL-6 signal transduction in prostate epithelial cells
| A. Staršíchová |
2008 - 2009 | MU Rektor?s Programme for Students? Creative Activity Support | Possibilities in modulation of neuroendocrine differentiation of prostate cancer cells
| Z. Pernicová |
Úkončené
year | grant agency/ grant number |
title | principal investigator/ coinvestigator | |||||
1993 | MŠMT V 316/93 | Introducing of the students into research programmes and teaching in IBP | J. Hofmanová A. Kozubík | |||||
1994 |
MŠMT | New teaching conception and realization of specific lectures.. | J. Hofmanová A. Kozubík | |||||
1995 |
MŠMT 252/95 | Introducing of students of Fac. Sci. in Brno into studies of the role of nutrition factors in tumor initiation and promotion |
J. Hofmanová A. Kozubík | |||||
1997 | MŠMT 298/97 | The role of cytokines and eicosanoids in regulation of cancer cell growth | J. Hofmanová A. Kozubík | |||||
1998 | MŠMT 805/98 | Animal physiology teaching within the phrame-work of new research trends .. | J. Hofmanová A. Kozubík | |||||
1993 - 1996 |
GAČR 505/93/2369 | The role of eicosanoids in regulation of proliferation and differentiation of mammalian cells |
A. Kozubík | |||||
1996 - 1998 |
GAČR 524/96/1716 | The role of cytokine TGF-b1 and eicosanoids in differentia -tion of mammalian progenitor cells |
A. Kozubík | |||||
1996 - 1998 |
GAČR 301/96/K 047 | Apoptotic death of tumor cells - mechanisms of regulation, detection and terapeutic applications | J. Hofmanová A. Kozubík | |||||
1999 - 2001 | GAČR 524/99/0694 | Polyunsaturated fatty acids and cytokines..... | A. Kozubík | |||||
1996 - 1998 | MŽP VaV 340/96 | Environmental risk assesment | A. Kozubík | |||||
1993 - 1997 | MHP
| Humine program | A. Kozubík J. Hofmanová | |||||
1995 - 1998 |
1015/SÚJV | Hemopoietic recovery and tumor cell proliferation in mice after irradiation under conditions of modulated eicosanoid metabolism |
A. Kozubík | |||||
1998 - 2000 |
GA ČR 525/98/1266 | Biochemical and cellular markers of toxic and carcinogenic effects of xenobiotics |
J. Hofmanová
| |||||
1998 - 2000 |
GAČR 312/98/PO11 | The role of arachidonic acid metabolism in apoptosis induced by TNFa and anti-Fas during differentiation of human leukemic cell line HL-60 |
J. Vondráček | |||||
1997 - 1999 |
IGA MZ 4095-3 | Metabolic and regulatory effects of lipids in arteficial nutrition | J. Hofmanová
| |||||
2000 | MŠMT | Support of studies of ?Cellular and molecular physiology? | J. Hofmanová A. Kozubík | |||||
2000 - 2002 |
IGA MZ | Changes of lipid metabolism and its mediator-related effects in patients with colorectal carcinoma....... |
J. Hofmanová
| |||||
2001 - 2003 | GA ČR 305/01/0418 | Cellular and molecular pharmacology of platinum and ruthenium anticancer drugs |
A. Kozubík | |||||
2001 - 2003 | GA ČR 525/01/0419 | Dietary lipid components in the regulation of cytokinetics of colonic epithelium |
J. Hofmanová | |||||
2000 - 2004 | IGA AV ČR S 5004009 | Untraditional therapeutic approaches in oncology |
A. Kozubík | |||||
2001 - 2004
|
GA ČR 524/01/D076 | Activation of Map protein kinase pathways by polycyclic aromatic hydrocarbons in vitro ? a potential nongenotoxic mechanism underlying the effects of environmental contaminants |
J. Vondráček | |||||
2002 - 2004 |
GA ČR 524/02/P051 | The interaction of cytokine TNF-a with butyrate during differentiation and apoptosis of colon epithelial cells |
M. Kovaříková | |||||
2003 - 2005 |
GA ČR 524/03/0766 | Modulation of proliferation, differentiation and apoptosis of hemopoietic cells ? interactions of cytokines, drugs and lipid nutrition compounds |
A. Kozubík | |||||
2003 - 2005 |
GA ČR 525/03/1527 | Chemical identification and in vitro screening of toxicity of aromatic contaminants in agricultural production environment. |
J. Vondráček
| |||||
2004 - 2006 |
GA ČR 524/04/0895 | Mechanisms of cell death induced by dietary lipid components and endogenous apoptotic regulators in colon epithelial cells
|
J. Hofmanová | |||||
2004 - 2006 |
IGA AV ČR B6004407 | Interactions of genotoxic and nongenotoxic effects of polycyclic aromatic hydrocarbons in... |
J. Vondráček | |||||
2005
|
FRVŠ 2528/2005 | High effectiveness of platinum(IV) complex with adamantylamine in overcoming resistance to cisplatin and suppressing proliferation of ovarian cancer cells in vitro |
V. Horváth
| |||||
2006 - 2007 | MU Rektor?s Programme for Students? Creative Activity Support 20061431C0007 |
Effects of cytostatics and xenobiotics on deregulation of cell proliferation and apoptosis |
J. Zatloukalová | |||||
2005 - 2007 |
IGA AV ČR KJB500040508
| Cell adhesion and anoikis of intestinal cells ? role of TNF family members, AA metabolism, and differentiation |
M. Hýžďalová
| |||||
2005 - 2007 |
GA ČR 524/05/0595 | Interactions of physiological growth regulators, arachidonic acid and xenobiotics |
A. Kozubík | |||||
2006 - 2007 |
ESF Olomouc | Zvýšení kvalifikace a flexibility absolventů doktorského studijního programu na LF UP | J. Hofmanová A. Kozubík J. Vondráček | |||||
2006 - 2007 |
KONTAKT (česko-slovenská vědeckotechnická spolupráce ) | Důsledek inhibice COX-2 v nádorových a nenádorových buňkách epitelu tlustého střeva, exponovaných fotocytotoxickému účinku hypericinu |
A. Kozubík P. Fedoročko
| |||||
2006 - 2008 |
GA ČR 524/06/0517 | Mechanisms of disruption of cell-to-cell communication and regulation of cell proliferation in liver cells |
J. Vondráček | |||||
2006 - 2008 |
GA ČR 524/06/P345 | Activity of inflammatory regulator NF-kappaB modulated by alteration of arachidonic acid metabolism |
J. Procházková | |||||
2007- 2008 | KONTAKT (česko-maďarská vědeckotechnická spolupráce) | Role of lipid rafts in regulation of cell signalling leading to modulation of cytokinetics of cancer cells |
A. Kozubík J. Szöllősi |