Projekty

 

Běžící

 

Title / Agency

investigator/

year

Lipid nutrition compounds-modulation of their effects and possibilities of practical application (IGA AVČR 1QS500040507)
A. Kozubík
2005 - 2009
Role of transforming growth factor-beta in regulation of proliferation, differentiation and apoptosis in prostate and colon cancer.
(GA ČR 204/07/0834)
K. Souček
2007 - 2009

2007 - 2010

GA ČR

310/07/0961

The role of environmental pollutants in mechanisms regulating development of prostate carcinoma

M. Machala

J. Topinka

K. Souček

2007 - 2011

GA ČR

301/07/1557

 

Novel anticancer platinum complexes ? mechanisms of their action and innovative chemotherapy

A. Kozubík

2007 - 2011

GA ČR

524/07/1178

Importance of cell lipid changes during differentiation and apoptosis of colon epithelial cells

J. Hofmanová

2009 - 2011

GAČR

524/09/1337

Interactions of Wnt and Ah receptor signaling in regulation of functions of liver cells

J. Vondráček

2009 - 2011

GAČR

305/09/1526

The role of extracellular matrix-mediated cell adhesion in maintenance of colonic tissue homeostasis and in colon carcinogenesis

M. Hýžďalová

2009 - 2011

GAČR

204/09/J030

Význam beta-arrestinu pro regulaci specificity ve Wnt signalizaci

V. Bryja

 

2009 - 2012

 

GAČR

204/09/H058

 

Intercellular signalling in development and disease

V. Bryja

J. Vondráček

M. Jindra

Z. Kozmik

M. A. Jindrová

2009 - 2012

GAČR

Molekulární mechanismy vybraných patologických procesů v buňce

P. Anzenbacher

J. Hofmanová

2008 - 2011

MZD 9600-4

Modulation of signaling pathways leading to neuroendocrine differentiation in prostate cancer

K. Souček

2008 - 2011

MZD 9956-4

 

Significance of asporin and other extracellular matrix proteins in invasive carcinomas of breast and prostate

J. Bouchal

K. Souček

2005 - 2008

LACHEMA

Project LA-12

A. Kozubík

2008 - 2009

MU  Rektors Programme for Students? Creative

 Activity Support

Differences of adhesive properties and anoikis regulation in colon cells during interaction of fatty acids with cytokines of TNF family

L. Kočí

2008 - 2009

MU  Rektor?s Programme for Students? Creative

 Activity Support

Role of TGFbeta family proteins in the cytokinetics of prostate and colon cancer cells

E. Lincová

2008 - 2009

MU  Rektor?s Programme for Students? Creative

 Activity Support

Modulation possibilities of cytokine IL-6 signal transduction in prostate epithelial cells

 

A. Staršíchová

2008 - 2009

MU  Rektor?s Programme for Students? Creative

 Activity Support

Possibilities in modulation of neuroendocrine differentiation of prostate cancer cells

 

Z. Pernicová

 

 

Úkončené

 

 

year

grant agency/

grant number

 

title

principal investigator/

coinvestigator

1993

MŠMT 

V 316/93

Introducing of the students into research programmes and teaching in IBP

J. Hofmanová

A. Kozubík

 

1994

 

MŠMT

New teaching conception and realization of specific lectures..

J. Hofmanová

A. Kozubík

 

1995

 

MŠMT

252/95

Introducing of students of Fac. Sci. in Brno into studies of the role of nutrition factors in tumor initiation and promotion

 

J. Hofmanová

A. Kozubík

 

1997

MŠMT

298/97

The role of cytokines and eicosanoids in regulation of cancer cell growth

J. Hofmanová

A. Kozubík

 

1998

MŠMT

805/98

Animal physiology teaching within the phrame-work of new research trends ..

J. Hofmanová

A. Kozubík

 

1993 - 1996

 

GAČR 505/93/2369

The role of eicosanoids in regulation of proliferation and differentiation of mammalian cells

 

A. Kozubík

 

1996 - 1998

 

GAČR  524/96/1716

The role of cytokine TGF-b1 and eicosanoids in  differentia -tion of mammalian progenitor cells

 

A. Kozubík

 

1996 - 1998

 

GAČR 301/96/K 047

Apoptotic death of tumor cells -  mechanisms of regulation, detection and terapeutic applications

J. Hofmanová

A. Kozubík

1999 - 2001

GAČR 524/99/0694

Polyunsaturated fatty acids and cytokines.....

A. Kozubík

1996 - 1998

MŽP

VaV 340/96

Environmental risk assesment

A. Kozubík

1993 - 1997

MHP

 

Humine program

A. Kozubík

J. Hofmanová

 

1995 - 1998

 

1015/SÚJV

Hemopoietic recovery and tumor cell proliferation in mice after irradiation under conditions of modulated eicosanoid metabolism

 

A. Kozubík

 

1998 - 2000

 

GA ČR 525/98/1266

Biochemical and cellular markers of toxic and carcinogenic effects of xenobiotics

 

J. Hofmanová

 

 

 

1998 - 2000

 

GAČR 312/98/PO11

The role of arachidonic acid metabolism in apoptosis induced by TNFa and anti-Fas during differentiation of human leukemic cell line HL-60

 

J. Vondráček

 

1997 - 1999

 

IGA MZ  4095-3

Metabolic and regulatory effects of lipids in arteficial nutrition

J. Hofmanová

 

2000

MŠMT
966/2000

Support of studies of ?Cellular and molecular physiology?

J. Hofmanová

A. Kozubík

 

 

2000 - 2002

 

IGA MZ
NC/6171-3

Changes of lipid metabolism and its mediator-related effects in patients with colorectal carcinoma.......

 

J. Hofmanová

 

 

 

2001 - 2003

GA ČR

305/01/0418

Cellular and molecular pharmacology of platinum and ruthenium anticancer drugs

 

A. Kozubík

 

 

2001 - 2003

GA ČR

525/01/0419

Dietary lipid components in the regulation of cytokinetics of colonic epithelium

 

J. Hofmanová

 

 

2000 - 2004

IGA AV ČR

S 5004009

Untraditional therapeutic approaches in oncology

 

A. Kozubík

 

 

 

 

2001 - 2004

 

 

 

GA ČR

524/01/D076

Activation of Map protein kinase pathways by polycyclic aromatic hydrocarbons in vitro ? a potential nongenotoxic mechanism underlying the effects of environmental contaminants

 

 

 

J. Vondráček

 

 

 

2002 - 2004

 

GA ČR

524/02/P051

The interaction of cytokine TNF-a  with  butyrate during differentiation and apoptosis of colon epithelial cells

 

 

M. Kovaříková

 

 

 

2003 - 2005

 

 

GA ČR

524/03/0766

Modulation of proliferation, differentiation and apoptosis of hemopoietic cells ? interactions of cytokines, drugs and lipid nutrition compounds

 

 

A. Kozubík

 

 

 

2003 - 2005

 

GA ČR

525/03/1527

Chemical identification  and in vitro screening of toxicity of aromatic contaminants in agricultural production environment.

 

 

J. Vondráček

 

 

 

 

2004 - 2006

 

GA ČR

524/04/0895

Mechanisms of cell death induced by dietary lipid components and endogenous apoptotic regulators in colon epithelial cells

 

 

 

J. Hofmanová

 

 

2004 - 2006

 

IGA AV ČR

B6004407

Interactions of genotoxic and nongenotoxic effects of polycyclic aromatic hydrocarbons in...

 

 

J. Vondráček

 

 

 

   2005

 

 

 

FRVŠ

2528/2005

High effectiveness of platinum(IV) complex with adamantylamine in overcoming resistance to cisplatin and suppressing proliferation of ovarian cancer cells in vitro

 

 

V. Horváth

 

 

 

 

 

 

2006 - 2007

MU  Rektor?s Programme for Students? Creative

 Activity Support

20061431C0007

 

Effects of cytostatics and xenobiotics on deregulation of cell proliferation and apoptosis

 

J. Zatloukalová

 

 

 

2005 - 2007

 

IGA AV ČR

KJB500040508

 

Cell adhesion and anoikis of intestinal cells ? role of TNF family members, AA metabolism, and differentiation

 

 

M. Hýžďalová

 

 

 

2005 - 2007

 

GA ČR

524/05/0595

Interactions of physiological growth regulators, arachidonic acid and xenobiotics

 

A. Kozubík

 

 

2006 - 2007

 

ESF Olomouc

Zvýšení kvalifikace a flexibility absolventů doktorského studijního programu na LF UP

J. Hofmanová

A. Kozubík

J. Vondráček

 

 

 

2006 - 2007

 

KONTAKT

(česko-slovenská vědeckotechnická spolupráce )

Důsledek inhibice COX-2 v nádorových a nenádorových buňkách epitelu tlustého střeva, exponovaných fotocytotoxickému účinku hypericinu

 

A. Kozubík

P. Fedoročko

 

 

 

 

2006 - 2008

 

GA ČR

524/06/0517

Mechanisms of disruption of cell-to-cell communication and regulation of cell proliferation in liver cells

 

J. Vondráček

 

 

2006 - 2008

 

GA ČR

524/06/P345

Activity of inflammatory regulator NF-kappaB modulated by alteration of arachidonic acid metabolism

 

J. Procházková

 

 

2007- 2008

KONTAKT

(česko-maďarská vědeckotechnická spolupráce)

Role of lipid rafts in regulation of cell signalling leading to modulation of cytokinetics of cancer cells

 

A. Kozubík

J. Szöllősi