Oxidizability of cysteine and short cysteine-containing peptides by molecular oxygen

Publikace: CHEMIA ANALITYCZNA 52, 979-988 Autoři: Dorcak, V., Mader, P., Vesela, V., Fedurco, M., Sestakova, I. Rok: 2007

Abstrakt

Rate of oxidation of cysteine, gamma-glutamylcysteine, cysteinylglycine and reduced glutathione by molecular oxygen has been studied polarographically in alkaline buffers by following the time changes in anodic and cathodic limiting currents of the SH- and SS-groups, respectively. Oxidation of thiols proceeds considerably faster in-contact with metallic mercury. Obtained results have been supported by Raman spectroscopy measurements.